Kyrle Disease Treatment & Management

Updated: Apr 18, 2017
  • Author: Mary Piazza Maiberger, MD; Chief Editor: William D James, MD  more...
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Medical Care

Kyrle disease perhaps is most important as a cutaneous sign of a systemic disorder, although idiopathic cases without associated systemic disease occur. Therefore, direct therapeutic efforts toward any underlying condition. For patients in whom itching is a major problem, soothing antipruritic lotions containing menthol and camphor may be helpful. Sedating antihistamines such as hydroxyzine may be helpful for pruritus, especially at night. Potent topical corticosteroids such as topical steroids may help coexisting prurigo nodularis and lichen simplex chronicus.

UV light therapy is considered by some authorities to be the most effective treatment for acquired perforating dermatosis and is particularly helpful for patients with widespread lesions or coexisting pruritus from renal or hepatic disease.


Surgical Care

Carbon dioxide laser or cryosurgery may be helpful for limited lesions. Caution must be exercised for individuals with dark skin, especially with cryosurgery, because of resulting dyspigmentation. Also, lesions on the lower legs, particularly in patients with diabetes mellitus or poor circulation may heal poorly.



Dermatologist or internal medicine specialist consultation may be necessary.