Denture Stomatitis Workup

Updated: Dec 06, 2020
  • Author: James J Sciubba, DMD, PhD; Chief Editor: Jeff Burgess, DDS, MSD  more...
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Laboratory Studies

A smear of the fungal material from the mucosa can be prepared and studied by using a potassium hydroxide (KOH) preparation or periodic acid-Schiff staining in the laboratory. Other methods of identifying fungal organisms involve the use of imprint cultures. [23]


Histologic Findings

Inflammatory papillary epithelial hyperplasia (IPEH) is not associated with cytologic signs of dysplasia. Epithelial dysplasia has not been observed in specimens of denture stomatitis.



The level of denture stomatitis can be classified as follows [24] :

  • Type I - Pinpoint hyperemia or localized simple inflammation

  • Type II - Diffuse erythema confined to the mucosa in contact with the denture base (see image below)

    A variably intense erythema distributed over the p A variably intense erythema distributed over the part of the mucosa covered by the denture base is diagnostic of denture stomatitis.
  • Type III - Granular surface or inflammatory papillary hyperplasia of the palate (see image below)

    When untreated and chronic, papillary epithelial h When untreated and chronic, papillary epithelial hyperplasia may develop. This may need to be surgically removed before the denture is replaced or relined.

Type III denture stomatitis involves the epithelial response to chronic inflammatory stimulation secondary to yeast colonization and, possibly, low-grade local trauma resulting from an ill-fitting denture.