Contact Stomatitis Medication

Updated: Dec 15, 2017
  • Author: Antonella Tosti, MD; Chief Editor: Dirk M Elston, MD  more...
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Medication

Medication Summary

Topical steroids are the first-line therapy for contact stomatitis. Available vehicles include topical gels, creams, pastes, ointments, sprays, and rinses. General guidelines for administration and usage can be found in standard pharmacology references.

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Corticosteroids

Class Summary

These agents have anti-inflammatory properties and cause profound and varied metabolic effects. Corticosteroids modify the body's immune response to diverse stimuli.

Triamcinolone topical (Aristocort)

Triamcinolone topical is for inflammatory dermatoses responsive to steroids; it decreases inflammation by suppressing the migration of polymorphonuclear leukocytes and reversing capillary permeability. Use 0.1% gel.

Fluocinonide (Fluonex, Lidex)

Fluocinonide is a high-potency topical corticosteroid that inhibits cell proliferation. It is immunosuppressive and anti-inflammatory. Use 0.05% gel.

Clobetasol (Temovate)

Clobetasol is a class I superpotent topical steroid; it suppresses mitosis and increases synthesis of proteins that decrease inflammation and cause vasoconstriction. Use 0.05% gel.

Prednisone (Deltasone)

Prednisone is an immunosuppressant for the treatment of autoimmune disorders; it may decrease inflammation by reversing increased capillary permeability and suppressing PMN activity. Prednisone stabilizes lysosomal membranes and suppresses lymphocyte and antibody production. It is useful in severe cases.

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