Angina Bullosa Hemorrhagica Differential Diagnoses

Updated: Sep 12, 2022
  • Author: Kara Melissa Torres Culala, MD; Chief Editor: Dirk M Elston, MD  more...
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Diagnostic Considerations

The most recent diagnostic criteria has been proposed by Ordioni et al [30] where a minimum of 6 out of 9 criteria should be met:

Table (Open Table in a new window)

Main criteria
(I) Clinically noticeable hemorrhagic bulla or erosion with a history of bleeding of the oral mucosa
(II) Exclusively oral or oropharyngeal localization
Additional criteria
(III)  Palatal localization
(IV) Triggering event or promoting factor (food intake)
(V)  Recurrent lesions
(VI) Favorable evolution without leaving a scar in a few days
(VII) Painless lesion, tingling, or burning sensation
(VIII) Normal platelet count and coagulation profile
(IX) Negative direct immunofluorescence

Differential Diagnoses