Surgical Care

Conservative excision is typically curative, although the lesion must be completely removed to prevent recurrence.^[12]In areas such as the maxillary gingivae where surgical removal may have a negative esthetic impact, the clinician may want to consider a gingival graft in conjunction with the excision of the lesion.^{[13, 14]}

Chrcanovic BR, Gomes CC, Gomez RS. Peripheral giant cell granuloma: An updated analysis of 2824 cases reported in the literature. J Oral Pathol Med. 2018 Mar 22. [Medline].
Bischof M, Nedir R, Lombardi T. Peripheral giant cell granuloma associated with a dental implant. Int J Oral Maxillofac Implants. 2004 Mar-Apr. 19(2):295-9. [Medline].
Hirshberg A, Kozlovsky A, Schwartz-Arad D, Mardinger O, Kaplan I. Peripheral giant cell granuloma associated with dental implants. J Periodontol. 2003 Sep. 74(9):1381-4. [Medline].
Cloutier M, Charles M, Carmichael RP, Sandor GK. An analysis of peripheral giant cell granuloma associated with dental implant treatment. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007. 103:618-622. [Medline].
Etoz OA, Demirbas AE, Bulbul M, Akay E. The peripheral giant cell granuloma in edentulous patients: report of three unique cases. Eur J Dent. 2010 Jul. 4(3):329-33. [Medline]. [Full Text].
Lester SR, Cordell KG, Rosebush MS, Palaiologou AA, Maney P. Peripheral giant cell granulomas: a series of 279 cases. Oral Surg Oral Med Oral Pathol Oral Radiol. 2014 Oct. 118 (4):475-82. [Medline].
Bodner L, Peist M, Gatot A, Fliss DM. Growth potential of peripheral giant cell granuloma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997 May. 83(5):548-51. [Medline].
Martins MD, Pires F, Daleck F, Myaki SI, Friggi MN, Martins MA. Peripheral giant cell granuloma in anterior maxilla: case report in a child. J Clin Pediatr Dent. 2005 Winter. 30(2):161-4. [Medline].
Dereci Ö, Akgün Ş, Celasun B, Öztürk A, Günhan Ö. Histological evaluation of the possible transformation of peripheral giant cell granuloma and peripheral ossifying fibroma: A preliminary study. Indian J Pathol Microbiol. 2017 Jan-Mar. 60 (1):15-20. [Medline].
Choi C, Terzian E, Schneider R, Trochesset DA. Peripheral giant cell granuloma associated with hyperparathyroidism secondary to end-stage renal disease: a case report. J Oral Maxillofac Surg. 2008 May. 66(5):1063-6. [Medline].
Dayan D, Buchner A, Spirer S. Bone formation in peripheral giant cell granuloma. J Periodontol. 1990 Jul. 61(7):444-6. [Medline].
Banthia R, Maheshwari S, Banthia P, Mantri K. Peripheral giant cell granuloma: a case report. Gen Dent. 2013 Jan-Feb. 61(1):e12-4. [Medline].
Sahingur SE, Cohen RE, Aguirre A. Esthetic management of peripheral giant cell granuloma. J Periodontol. 2004 Mar. 75(3):487-92. [Medline].
Said Ahmed W. Efficacy of Ethanolamine Oleate Sclerotherapy in Treatment of Peripheral Giant Cell Granuloma. J Oral Maxillofac Surg. 2016 Nov. 74 (11):2200-2206. [Medline].

Media Gallery

A 10-year-old boy developed this painless purple papule of the maxillary facial alveolar process over a 3-month period. Biopsy helped confirm the diagnosis of peripheral giant cell granuloma.
This peripheral giant cell granuloma involved the maxillary gingiva associated with an erupting central incisor of a 6-year-old girl. The referring doctor had suggested a diagnosis of eruption cyst; however, an eruption cyst would immediately collapse once the tooth had disrupted its roof.
This asymptomatic bluish-purple nodule developed on the edentulous mandibular alveolar ridge of a 76-year-old man.