Oral Melanoacanthoma Treatment & Management

Updated: Feb 12, 2021
  • Author: Claudia C Cotca, DDS, MPH; Chief Editor: Jeff Burgess, DDS, MSD  more...
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Medical Care

No medical treatment for mucosal or cutaneous lesions is known. A low risk of recurrence exists. In patients with mucosal lesions, treatment may be limited to removal of the precipitating stimulus. [28] Lesions spontaneously resolve in approximately 40% of patients with oral lesions. [2]


Surgical Care

Surgical excision is the treatment of choice for both mucosal and cutaneous lesions. Because rare cases of premalignant or malignant cutaneous lesions are reported, wider resection with clear margins is recommended. In benign cutaneous melanoacanthoma, local excision or ablation of the site is adequate. If mucosal lesions do not resolve, local excision or ablation is indicated.

Cryosurgery, electrosurgery, or laser treatment [29] may be used to remove lesions; however, these modalities may jeopardize the microscopic diagnosis. Specific laser utilization must be stated on the biopsy order.



No evidence of malignant transformation has been reported. No complications arise from incisional or excisional biopsy.