Erythema Gyratum Repens Workup

Updated: Mar 27, 2019
  • Author: Nicole Ufkes; Chief Editor: Dirk M Elston, MD  more...
  • Print
Workup

Laboratory Studies

A basic workup is warranted when approaching a patient with erythema gyratum repens to search for common or clinically suspected malignancies. This includes the following:

  • Complete physical examination (including pelvic examination and Papanicolaou test [Pap smear] for women, prostate examination and prostate-specific antigen test for men)

  • Urinalysis

  • Basic hematologic panel

  • Blood chemistries (including liver function test, calcium, phosphorus, total protein)

  • Stool guaiac and/or Hemoccult test

Next:

Imaging Studies

Examine patients with erythema gyratum repens for common or clinically suspected malignancies. This workup can include chest radiography and CT scanning of the abdomen and pelvis.

Previous
Next:

Procedures

Necessary procedures may include the following:

  • Esophagogastroduodenoscopy

  • Ear, nose, and throat examination (for malignancy)

Previous
Next:

Histologic Findings

The primary finding is mild spongiosis, focal parakeratosis, and a superficial perivascular lymphohistiocytic infiltrate that also may include eosinophils and melanophages. Exocytosis of neutrophils and eosinophils may be observed. Direct immunofluorescence tests sometimes reveal C3, C4, and immunoglobulin G at the basement membrane zone. [32]

Previous