Erythema Nodosum Treatment & Management

Updated: May 11, 2020
  • Author: Jeanette L Hebel, MD; Chief Editor: William D James, MD  more...
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Treatment

Medical Care

In most patients, erythema nodosum is a self-limited disease and requires only symptomatic relief using nonsteroidal anti-inflammatory drugs (NSAIDs), cool wet compresses, elevation, and bed rest.

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Consultations

Consultations with a dermatologist and/or internist may be necessary for evaluation of the underlying cause of erythema nodosum.

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Activity

Patient mobility is restricted in the acute stages if pain and swelling are significant.

Compression stockings may be beneficial to decrease swelling and allow patients to maintain their normal activity level. [22]

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Prevention

Restriction of physical activities while erythema nodosum is active may prevent exacerbations of the disease.

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Long-Term Monitoring

The course of erythema nodosum is benign and self-limited. Bed rest and restriction of physical activities is encouraged during the active phase.

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