Cold Panniculitis Workup

Updated: Apr 28, 2020
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
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Workup

Laboratory Studies

For cold panniculitis (CP), a clinical diagnosis often can be made.

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Procedures

Biopsy is reserved for diagnostic problem cases. Punch biopsies usually are inadequate. Deep skin incisional biopsies are required to adequately sample the subcutaneous tissue. Findings are localized to the subcutaneous tissue.

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Histologic Findings

The classic features of cold panniculitis on histopathology predominantly are a lobular panniculitis with scattered lymphohistiocytic and eosinophilic infiltrates. The deposition of mucin is a special finding.

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