Dermatologic Manifestations of Kaposi Sarcoma Differential Diagnoses

Updated: Mar 29, 2023
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
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Diagnostic Considerations

Early stage Kaposi sarcoma (KS) is frequently atypical in presentation, causing diagnostic challenges. [56]

Also consider the following:

  • Cavernous hemangioma

  • Angiokeratoma

  • Carcinoma cutis (especially renal cell carcinoma)

  • Nodal myofibromatoma

  • Arteriovenous malformations (pseudo-Kaposi sarcoma)

  • Severe stasis dermatitis (pseudo-Kaposi sarcoma)

  • Kaposiform lymphangiomatosis [58]

  • Microvenular hemangioma [59]

  • Cutaneous vasculitis [60]

Acral pseudolymphomatous angiokeratoma of children may resemble Kaposi sarcoma clinically, including showing a rainbow pattern with dermatoscopy. [61]

Differential Diagnoses