Pigmented Purpuric Dermatosis Medication

Updated: Aug 12, 2019
  • Author: Darius Mehregan, MD; Chief Editor: Dirk M Elston, MD  more...
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Medication

Medication Summary

The goals of pharmacotherapy are to reduce morbidity and to prevent complications.

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Corticosteroids

Class Summary

These agents are effective in relieving pruritus. These agents have anti-inflammatory properties and cause profound and varied metabolic effects. They modify the body's immune response to diverse stimuli.

Hydrocortisone topical (Westcort)

Hydrocortisone topical is an adrenocorticosteroid derivative suitable for application to skin or external mucous membranes. It has mineralocorticoid and glucocorticoid effects, resulting in relief of pruritus.

Clobetasol (Temovate)

Clobetasol is a class I superpotent topical steroid; it suppresses mitosis and increases the synthesis of proteins that decrease inflammation and cause vasoconstriction.

Betamethasone topical (Diprolene, Betatrex)

Betamethasone topical is for inflammatory dermatoses responsive to steroids. It decreases inflammation by suppressing the migration of polymorphonuclear leukocytes and reversing capillary permeability.

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Antihistamines

Class Summary

These agents may treat itching by blocking effects of endogenously released histamine.

Diphenhydramine (Benadryl, Benylin, Diphen, AllerMax)

Diphenhydramine is for symptomatic relief of pruritus caused by the release of histamine in inflammatory reactions.

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