Pigmented Purpuric Dermatosis Treatment & Management

Updated: Aug 12, 2019
  • Author: Darius Mehregan, MD; Chief Editor: Dirk M Elston, MD  more...
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Treatment

Medical Care

No medical intervention is of consistent benefit for the treatment of the pigmented purpuric dermatoses.

Pruritus may be alleviated by the use of topical corticosteroids and antihistamines.

Associated venous stasis should be treated by compression hosiery.

Prolonged leg dependency should be avoided.

The use of narrowband UVB and psoralen plus UVA have shown to be effective treatments for some patients with pigmented purpuric dermatoses. [22, 23, 24, 25, 26]

Tamaki et al reported successful treatment of pigmented purpuric dermatoses using griseofulvin. [27] Treatment with oral cyclosporin has also been successful. [28]

Successful therapy with ascorbic acid (500 mg twice daily) and rutoside (50 mg twice daily) has also been reported. [29] Anecdotal data exist for calcineurin-inhibitors, colchicine, pentoxifylline, immunosuppressants, ultraviolet therapy, and laser therapy. [30]

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Long-Term Monitoring

A follow-up consultation is required for cases in which initially diagnostic uncertainty exists, particularly to exclude cutaneous lymphoma.

Topical steroid treatment if used long term should be monitored for the possible development of adverse effects.

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