Mondor Disease Clinical Presentation

Updated: Apr 07, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
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Mondor disease is most often observed as a cordlike indurated plaque on the upper anterolateral aspect of the chest wall. [18, 20] No systemic symptoms are usually present, although rarely there may be chest pain. [21]

Ask the patient about the following:

  • Recent breast surgery: In one report, 7 of 15 patients had a radical mastectomy prior to the onset of Mondor thrombophlebitis on the ipsilateral side. [22] Mondor disease may occur after breast reduction surgery. [23]

  • Possible physical strain, [24] as might be experienced by bodybuilders [8]

  • Tight dressings and tight-fitting bras [25]

  • Axillary shaving [26]

  • Blood dyscrasia [27]

Subcutaneous penile vein thrombosis of other sites has also been described. [2] It is first evident as sudden and almost painless indurations on the penile dorsal surface. [28] In the axillae, it may occur after axillary lymph node dissection and sentinel lymph node biopsy. [5]


Physical Examination

Mondor disease has a characteristic clinical picture of a sudden appearance of a linear, cordlike, thrombosed vein. At first, this vein is red and tender, and then, it subsequently changes into a painless, tough, fibrous band. The cord is accentuated by traction, elevation of the breast, or abduction of the ipsilateral arm. It may also be evident as retracted breast skin. [29]

If the patient does not seek medical attention upon the initial presentation, the tenderness gradually subsides, while the thrombus organizes and recanalizes, leaving a nontender, hard, ropelike band. This band remains for varying periods up to several weeks. [6]



Mondor phlebitis is not migratory and does not recur.