Erythema Ab Igne

Updated: Oct 04, 2016
  • Author: Laila I Al-Otaibi, MBBCh, MSc; Chief Editor: Dirk M Elston, MD  more...
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Erythema ab igne (EAI) is characterized as localized areas of reticulated erythema and hyperpigmentation due to chronic and repeated exposure to infrared radiation. Patients with erythema ab igne have a history of repeated exposures to heat at a lower level than that which causes a thermal burn. [1] Other terms used to describe erythema ab igne include toasted skin syndrome and fire stains. [2]

Initially, the skin in erythema ab igne patients is often mildly erythematous; however, after repeated heat exposures, the classic blue, purple, or brown reticulated hyperpigmentation develops. [1]  See the image below.

Red rash resembling lacework or a fishing net on b Red rash resembling lacework or a fishing net on back.


Erythema ab igne (EAI) is a reticulate hypermelanosis with erythema resulting from repeated heat exposure that induces injury to the epidermis and superficial vascular plexus. The exposure, which need not be of long duration, results in cutaneous hyperthermia in the range of 43-47°C. Erythema ab igne results in histopathologic changes similar to those seen in solar-damaged skin. Although the pathogenic mechanisms in erythema ab igne are poorly understood, one study has shown that moderate heat acts synergistically with ultraviolet radiation to denature DNA in squamous cells in vitro. [3]




United States

Erythema ab igne is rare. Because of the general availability of central heating, erythema ab igne is less common in the United States than in countries where open fires are commonly used for heating.

Historically, erythema ab igne was often seen on the inner thighs and legs of women who sat in front of a stove or open fire. [1, 4] Now erythema ab igne is more commonly related to heating pads or laptop computer use.


Currently, erythema ab igne is most commonly seen internationally following repeated use of hot water bottles, infrared lamps, and heating pads. Additionally, chronic pain in the lumbosacral region and consequent repeated and prolonged use of localized heat to relieve those symptoms has led to an increased incidence of erythema ab igne in this area. [5, 6, 7]

Studies have shown that physiotherapeutic treatments use ultrasound and short-wave diathermy to promote (via high-frequency mechanical waves) an extremely rapid vibration in the tissues in order to generate heat and consequent dilation of the local veins to provide pain relief. [8]


Erythema ab igne has no overt racial predisposition.


Women, in particular those who are overweight, are affected by erythema ab igne more often than men. [1]


Erythema ab igne primarily occurs in adults, usually of middle age (40-70 y).



The prognosis is good, except those cases associated with internal disease or metastatic malignancy. Early changes, such as erythema and little or no hyperpigmentation, may resolve within several months. Chronic and repeated exposure to heat may result in permanent changes such as hyperpigmentation and atrophy. In addition, thermal keratosis, squamous cell carcinoma in situ, and squamous cell carcinoma have been reported within the lesions of erythema ab igne.


Chronic repeated exposure to infrared radiation may result in changes similar to those seen with chronic repeated ultraviolet radiation. Carcinoma can develop from dysplastic keratinocytes harbored within the reticulated hyperpigmentation. Thermal keratosis, squamous cell carcinoma in situ, and squamous cell carcinoma have been reported in patients after chronic exposure to infrared radiation. [9] In one 90-year-old woman with erythema ab igne, Merkel cell carcinoma developed adjacent to squamous cell carcinoma. Occasionally, the first sign of splenomegaly, pancreatitis, pancreatic cancer, and other cancers is erythema ab igne resulting when patients apply external heat to relieve the underlying pain. [4]

Work exposure to heat (eg, for bakers, silversmiths, and boiler operators) may cause erythema ab igne. [1] Additionally, erythema ab igne has been reported to appear on the legs following prolonged, daily exposure to a car heater.


Patient Education

Explain the etiology of the disorder to patients, and emphasize that the cessation of heat exposure is paramount. Inform patients with erythema ab igne about the possibility of malignant degeneration in the affected areas. Educate patients about detection and the need for prompt treatment.