Corns (Clavus) Workup

Updated: Feb 28, 2023
  • Author: Nanette B Silverberg, MD; Chief Editor: Dirk M Elston, MD  more...
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Histologic Findings

Corns demonstrate epidermal hyperplasia with a thick and compact stratum corneum. Whereas calluses demonstrate only orthokeratosis, parakeratosis may be present in corns, and biopsy specimens demonstrate an endophytic cup shape. The granular cell layer may be decreased or absent. [12, 15] The dermis may occasionally show fibrosis with hypertrophied nerves and scar tissue replacing subcutaneous fat. [12]