Muir-Torre Syndrome Medication

Updated: Oct 01, 2020
  • Author: Victor G Prieto, MD, PhD; Chief Editor: Dirk M Elston, MD  more...
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Medication

Medication Summary

The goals of pharmacotherapy for Muir-Torre syndrome (MTS) are to prevent development of neoplasms, reduce morbidity, and prevent complications.

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Retinoids

Class Summary

These agents regulate cell growth and proliferation. They may prevent some of the neoplasms in MTS.

Isotretinoin (Amnesteem, Claravis, Myorisan, Absorica)

Isotretinoin is an oral agent that treats serious dermatologic conditions. It is a synthetic 13-cis isomer of naturally occurring tretinoin (trans- retinoic acid). Both agents are structurally related to vitamin A.

A US Food and Drug Administration–mandated registry is now in place for all individuals prescribing, dispensing, or taking isotretinoin. For more information on this registry, see iPLEDGE. This registry aims to further decrease the risk of pregnancy and other unwanted and potentially dangerous adverse effects during a course of isotretinoin therapy.

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