Muir-Torre Syndrome Questions & Answers

Updated: Oct 01, 2020
  • Author: Victor G Prieto, MD, PhD; Chief Editor: Dirk M Elston, MD  more...
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Questions & Answers

Overview

What is Muir-Torre syndrome?

What is the pathophysiology of Muir-Torre syndrome?

What causes Muir-Torre syndrome?

What is the prevalence of Muir-Torre syndrome?

What are the sexual predilections of Muir-Torre syndrome?

Which age groups have the highest prevalence of Muir-Torre syndrome?

What is the prognosis of Muir-Torre syndrome?

What is included in patient education about Muir-Torre syndrome?

Presentation

Which clinical history findings are characteristic of Muir-Torre syndrome?

What are the diagnostic criteria for Muir-Torre syndrome?

Which physical findings indicate Muir-Torre syndrome?

DDX

Which conditions should be included in the differential diagnoses of Muir-Torre syndrome?

What are the differential diagnoses for Muir-Torre Syndrome?

Workup

What is the role of lab testing in the workup of Muir-Torre syndrome?

What is the role of imaging studies in the workup of Muir-Torre syndrome?

What is the role of sentinel lymph node assessment in the diagnosis of Muir-Torre syndrome?

Which histologic findings are characteristic of sebaceous adenoma in Muir-Torre syndrome?

Which histologic findings are characteristic of sebaceous epithelioma in Muir-Torre syndrome?

Which histologic findings are characteristic of sebaceous carcinoma in Muir-Torre syndrome?

Which histologic findings are characteristic of keratoacanthoma in Muir-Torre syndrome?

Which histologic finding in Muir-Torre syndrome is similar to Paget disease?

Which histologic findings are characteristic of sebaceous neoplasms in Muir-Torre syndrome?

Treatment

How is Muir-Torre syndrome treated?

What is the role of surgery in the treatment of Muir-Torre syndrome?

What is included in long-term monitoring of patients with Muir-Torre syndrome?

Medications

What are the goals of drug treatment for Muir-Torre syndrome?

Which medications in the drug class Retinoids are used in the treatment of Muir-Torre Syndrome?