Dermatologic Aspects of Addison Disease Differential Diagnoses

Updated: Jul 18, 2017
  • Author: Elizabeth A Liotta, MD; Chief Editor: William D James, MD  more...
  • Print
DDx

Diagnostic Considerations

Also consider the following:

Pregnancy increases the physiologic stress on the patient. The diagnosis of Addison disease may be delayed in pregnant women because the presenting symptoms of nausea, vomiting, and skin hyperpigmentation may be confused with symptoms of pregnancy. Glucocorticoid and mineralocorticoid doses may need to be adjusted in patients who are pregnant. For example, the fludrocortisone dose may need to be decreased if preeclampsia develops. Glucocorticoid and mineralocorticoid doses may need to be increased, especially during labor. Commonly, 1-3 doses of hydrocortisone 100 mg are intramuscularly or intravenously administered during labor.

Differential Diagnoses