POEMS Syndrome Medication

Updated: Sep 17, 2020
  • Author: Joanna L Chan, MD; Chief Editor: Dirk M Elston, MD  more...
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Medication Summary

The goal of pharmacotherapy is to reduce morbidity in patients whose disease does not respond to surgical removal or radiation therapy of the plasmacytoma.



Class Summary

These agents have anti-inflammatory properties and cause profound and varied metabolic effects. In addition, they modify the body's immune response to diverse stimuli.

Prednisone (Deltasone, Orasone, Meticorten)

Prednisone is useful in many inflammatory and autoimmune conditions. It must be metabolized to the active metabolite prednisolone for effect. Conversion may be impaired by liver disease. Prednisone may decrease inflammation by reversing increased capillary permeability and suppressing PMN activity.