Florid Cutaneous Papillomatosis Differential Diagnoses

Updated: Apr 16, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
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Diagnostic Considerations

Verrucous mycosis fungoides may occasionally require distinction. Verrucous mucocutaneous acanthosis nigricans of the lips and buccal mucosa may represent, as described by Pentenero et al [27] in 2004, a patient with underlying cancer also beginning to develop florid cutaneous papillomatosis (FCP).

Florid papillomatosis of the nipple has been described, a change reminiscent of the hyperkeratosis of nipple sometimes associated with acanthosis nigricans. [28, 29] Histologically, florid papillomatosis of nipple represented an adenoma.

FCP would not be confused with oral florid papillomatosis. [30]

Differential Diagnoses