Necrolytic Acral Erythema Questions & Answers

Updated: Jun 25, 2020
  • Author: Fnu Nutan, MD, FACP; Chief Editor: Dirk M Elston, MD  more...
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Questions & Answers

Overview

What is necrolytic acral erythema (NAE)?

What is the pathophysiology of necrolytic acral erythema (NAE)?

What causes necrolytic acral erythema (NAE)?

What is the prevalence of necrolytic acral erythema (NAE) in the US?

What is the global prevalence of necrolytic acral erythema (NAE)?

What are the racial predilections of necrolytic acral erythema (NAE)?

What are the sexual predilections of necrolytic acral erythema (NAE)?

Which age groups have the highest prevalence of necrolytic acral erythema (NAE)?

What is the prognosis of necrolytic acral erythema (NAE)?

Presentation

Which clinical history findings are characteristic of necrolytic acral erythema (NAE)?

Which physical findings are characteristic of necrolytic acral erythema (NAE)?

What are the stages of necrolytic acral erythema (NAE)?

Which areas of the body are not affected by necrolytic acral erythema (NAE)?

Which epiphenomenal conditions associated with hepatitis C should be considered in the differential diagnoses of necrolytic acral erythema (NAE)?

What are the possible complications of necrolytic acral erythema (NAE)?

DDX

Which conditions are included in the differential diagnoses of necrolytic acral erythema (NAE)?

What are the differential diagnoses for Necrolytic Acral Erythema?

Workup

What is the role of lab tests in the workup of necrolytic acral erythema (NAE)?

What is the role of imaging studies in the workup of necrolytic acral erythema (NAE)?

What is the role of biopsy in the workup of necrolytic acral erythema (NAE)?

Which histologic findings suggest necrolytic acral erythema (NAE) caused by zinc deficiency?

Which histologic findings are characteristic of the early stage of necrolytic acral erythema (NAE)?

Which histologic findings are characteristic of the fully-evolved stage of necrolytic acral erythema (NAE)?

Which histologic findings are characteristic of the late stage of necrolytic acral erythema (NAE)?

Which histologic findings are characteristic of necrolytic acral erythema (NAE) in patients with nutritional deficiency?

Which electron microscopy findings have been reported in patients with necrolytic acral erythema (NAE)?

How is necrolytic acral erythema (NAE) staged?

Treatment

How is necrolytic acral erythema (NAE) treated?

What is the role of surgery in the treatment of necrolytic acral erythema (NAE)?

Which specialist consultations are beneficial to patients with necrolytic acral erythema (NAE)?

Which dietary modifications are used in the treatment of necrolytic acral erythema (NAE)?

Which activity modifications are used in the treatment of necrolytic acral erythema (NAE)?

How is necrolytic acral erythema (NAE) prevented?

Medications

Which medications are used in the treatment of necrolytic acral erythema (NAE)?

Which medications in the drug class Nucleoside Analogs are used in the treatment of Necrolytic Acral Erythema?

Which medications in the drug class Interferons are used in the treatment of Necrolytic Acral Erythema?

Which medications in the drug class Minerals are used in the treatment of Necrolytic Acral Erythema?