Jessner Lymphocytic Infiltration of the Skin Medication

Updated: Dec 13, 2017
  • Author: Kara Melissa T Torres, MD, DPDS; Chief Editor: William D James, MD  more...
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Medication

Medication Summary

The goals of pharmacotherapy are to reduce morbidity and prevent complications.

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Corticosteroids

Class Summary

These agents have anti-inflammatory properties and cause profound and varied metabolic effects. They modify the body's immune response to diverse stimuli. Oral corticosteroids should only be used in severe unremitting disease not responsive to other treatment.

Hydrocortisone valerate (Westcort)

Hydrocortisone valerate is an anti-inflammatory adrenocorticosteroid derivative suitable for application to skin or external mucous membranes. It may alleviate pruritus and speed the resolution of lesions. Hydrocortisone valerate is available as a 0.2% cream or ointment.

Triamcinolone topical (Aristocort ointment, Kenalog cream)

Topical triamcinolone is for inflammatory dermatoses responsive to steroids; it decreases inflammation. An intramuscular injection may be used for widespread skin disorders, or intralesional injections may be used for localized skin disorders.

Betamethasone topical (Diprosone lotion)

Topical betamethasone is for inflammatory dermatoses responsive to steroids; it decreases inflammation. Betamethasone is available as a 0.05% cream or ointment.

Prednisone (Deltasone, Orasone)

Prednisone is used for treating lymphocytic infiltration of the skin, when taken orally, and is used alone or in combination with topical or intralesional steroids. It may decrease inflammation by reversing increased capillary permeability and suppressing PMN activity.

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Antimalarials

Class Summary

Antimalarials are used to treat certain photosensitive eruptions, including lymphocytic infiltration of the skin.

Hydroxychloroquine (Plaquenil)

Hydroxychloroquine's mechanism of action is not fully understood. Theories include light filtration, immunosuppression, anti-inflammatory action, and DNA binding. It is supplied as 200-mg tablets.

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