Cutaneous Pseudolymphoma Medication

Updated: Aug 14, 2019
  • Author: Gauri Panse, MBBS, MD; Chief Editor: William D James, MD  more...
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Medication

Medication Summary

The goals of pharmacotherapy for cutaneous pseudolymphoma are to reduce morbidity and to prevent complications.

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Corticosteroids

Class Summary

These agents have anti-inflammatory properties and cause profound and varied metabolic effects. In addition, these agents modify the body’s immune response to diverse stimuli.

Hydrocortisone valerate 0.2% (Ala Cort, HydroSKIN, Locoid, Pandel, NuZon, Dermasorb, NuCort, Rederm, Westcort)

Hydrocortisone valerate is an adrenocorticosteroid derivative suitable for application to skin or external mucous membranes. It has mineralocorticoid and glucocorticoid effects, resulting in anti-inflammatory activity. It is used to treat inflammatory dermatosis responsive to steroids. Hydrocortisone valerate decreases inflammation by suppressing the migration of polymorphonuclear leukocytes and reversing capillary permeability.

Betamethasone topical (Alphatrex, BetaVal, Dermabet)

Betamethasone is for inflammatory dermatosis responsive to steroids. It decreases inflammation by suppressing the migration of polymorphonuclear leukocytes and reversing capillary permeability.

Clobetasol (Temovate, Clobex, Clux)

Clobetasol is a class I superpotent topical steroid; it suppresses mitosis and increases the synthesis of proteins that decrease inflammation and cause vasoconstriction.

Fluocinonide (Vanos)

Fluocinonide is a high-potency topical corticosteroid that inhibits cell proliferation; it is immunosuppressive and anti-inflammatory.

Desonide (DesOwen, Verdeso, LoKara)

Desonide stimulates the synthesis of enzymes that decrease inflammation. It suppresses mitotic activity and causes vasoconstriction.

Fluocinolone (Capex, Derma-Smoothe/FS, Synalar)

Fluocinolone is a fluorinated corticosteroid of moderate potency at the 0.025% concentration and low potency at the 0.01% concentration (class 6). It has anti-inflammatory, antipruritic, and vasoconstrictive properties.

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