Angioimmunoblastic T-Cell Lymphoma Differential Diagnoses

Updated: Apr 24, 2020
  • Author: Amira M Elbendary, MBBCh, MSc; Chief Editor: Dirk M Elston, MD  more...
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DDx

Diagnostic Considerations

Angioimmunoblastic T-cell lymphoma (AITL) must be distinguished from reactive processes that mimic it. [36] AITL is usually diagnosed at advanced stages because its symptoms are nonspecific; thus, in older people, so-called B symptoms (ie, fever, weight loss, lymphadenopathy) should prompt investigation for AITL, leukemia, and lymphoma.

Reactive processes can mimic AITL; moreover, infections can occur with AITL, and AITL can evolve into high-grade lymphoma. These situations should be considered when assessing and treating AITL.

Other problems to be considered in patients with possible AITL include the following: