Premalignant Fibroepithelial Tumor (Pinkus Tumor) Clinical Presentation

Updated: Feb 08, 2019
  • Author: Darius Mehregan, MD; Chief Editor: Dirk M Elston, MD  more...
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The tumor can present alone or in association with seborrheic keratoses and/or other basal cell carcinomas.

Its frequency is higher in areas of prior radiation-damaged epidermis. [9]

Reports have described two women who had an associated malignancy. One was found to have intraductal breast carcinoma underlying the fibroepithelioma of Pinkus, [11] and the other was found to have a perianal fibroepithelioma harboring Paget cells. [12]


Physical Examination

The fibroepithelioma of Pinkus usually presents as a slowly enlarging, fleshy, raised or pedunculated papilloma or sessile fibroma with a broad base, most commonly on the trunk or the extremities.

The color is usually pink or reddish, but, in some instances, a tinge of brown may be present.

It may be single or multiple and shows a strong predilection for the lumbosacral area. However, numerous cases have occurred elsewhere, including the head, the abdomen, the anus, the penis, [13] the breasts, and the scrotum.

This tumor can clinically resemble seborrheic keratosis, pedunculated fibroma, nevus sebaceus of Jadassohn, papillomatous melanocytic nevus, amelanotic melanoma, and neurofibroma.

Dermoscopy shows fine arborizing vessels alone or associated with dotted vessels and white streaks. Gray-brown areas of pigmentation and variable gray-blue dots may be observed. [14] A white reticulated network has also been described, but this may also be seen in nevi, dermatofibroma, and melanoma. [15]



Fibroepithelioma of Pinkus can be classified as malignant with a low metastatic potential.