Eccrine Carcinoma Treatment & Management

Updated: Sep 22, 2016
  • Author: Georgina Marie Ferzli, MD, MS; Chief Editor: Dirk M Elston, MD  more...
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Treatment

Approach Considerations

The literature on treatment of eccrine carcinomas is very sparse.

While surgery remains the treatment of choice, some cases of distant metastases have been treated with radiation therapy. [7]

In one radiotherapy-resistant case of eccrine carcinoma, brachytherapy was used. [21]

Data on the use of chemotherapy for eccrine carcinoma is sparse, and it has not yet proved to be successful for the few listed cases in the literature. [22, 23, 24]

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Surgical Care

The treatment of choice is surgical excision of the tumor with negative margins, either by radical surgical excision or Mohs micrographic surgery. [25] As eccrine carcinomas tend to be locally infiltrating and have a propensity for perineural invasion, wide excision is recommended. [25] However, while the clinical experience is limited, the use of Mohs micrographic surgery appears to decrease recurrence rates compared with surgical excision. [18]

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Consultations

Surgical oncologists, medical oncologists, and interventional radiologists may play roles in the treatment of patients with eccrine carcinoma.

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