Overview
What is the pathophysiology of onycholysis?
Which medications are associated with non-photo-induced onycholysis?
Which systemic diseases are associated with onycholysis?
Which dermatologic diseases are associated with onycholysis?
Which neoplastic disorders are associated with onycholysis?
What are the nonmicrobial causes of onycholysis?
What are microbial causes of onycholysis?
Which medications are associated with photo-induced onycholysis?
What are the causes of non-medication photo-induced onycholysis?
What are the types of onycholysis?
What is the global incidence of onycholysis?
What are the racial predilections of onycholysis?
What are the sexual predilections of onycholysis?
Which age groups are at highest risk for onycholysis?
What is the prognosis of onycholysis?
What is included in patient education about onycholysis?
Presentation
Which physical findings are characteristic of onycholysis?
Workup
What is the role of lab testing in the diagnosis of onycholysis?
Which histological findings are characteristic of onycholysis?
Treatment
What is the role of intralesional injection in the treatment of onycholysis?
What should patients with onycholysis avoid?
Medications
What is the role of topical agents in the treatment of onycholysis?
Which medications in the drug class Corticosteroids are used in the treatment of Onycholysis?
Which medications in the drug class Antifungals are used in the treatment of Onycholysis?
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Thumb onycholysis. Courtesy of DermNet New Zealand (http://www.dermnetnz.org/assets/Uploads/hair-nails-sweat/olysis1.jpg).
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Great toe onycholysis. Courtesy of Professor Raimo Suhonen and DermNet New Zealand (http://www.dermnetnz.org/assets/Uploads/hair-nails-sweat/s/olysis7.jpg).