Confluent and Reticulated Papillomatosis Questions & Answers

1. Elinkichari D, Jaber K, Rabhi F, Dhaoui R. Confluent and reticulated papillomatosis of Gougerot-Carteaud in a North African patient. Clin Case Rep. 2022 Feb. 10 (2):e05394. [QxMD MEDLINE Link]. [Full Text].

2. Min ZS, Tan C, Xu P, Zhu WY. Confluent and reticulated papillomatosis manifested as vertically rippled and keratotic plaques. Postepy Dermatol Alergol. 2014 Oct. 31 (5):335-7. [QxMD MEDLINE Link].

3. Ibekwe PU, Ukonu BA. Punctate, pigmented, and verrucous papillomatosis: a rare variant of Gougerot-Carteaud syndrome. Int J Dermatol. 2015 Sep 4. [QxMD MEDLINE Link].

4. Morales-Cardona CA, Tejada-Figueroa C, Méndez-Velasco DM. Confluent and Reticulated Papillomatosis With Linear Pseudo-striae: A Description of 20 Cases. Actas Dermosifiliogr. 2017 Mar 2. [QxMD MEDLINE Link].

5. Bernardes Filho F, Quaresma MV, Rezende FC, Kac BK, Nery JA, Azulay-Abulafia L. Confluent and reticulate papillomatosis of Gougerot-Carteaud and obesity: dermoscopic findings. An Bras Dermatol. 2014 May-Jun. 89(3):507-9. [QxMD MEDLINE Link]. [Full Text].

6. Krueger L, Saizan A, Stein JA, Elbuluk N. Dermoscopy of acquired pigmentary disorders: a comprehensive review. Int J Dermatol. 2022 Jan. 61 (1):7-19. [QxMD MEDLINE Link].

7. Bhagwat PV, Tophakhane RS, Shashikumar BM, Noronha TM, Naidu V. Three cases of Dowling Degos disease in two families. Indian J Dermatol Venereol Leprol. 2009 Jul-Aug. 75(4):398-400. [QxMD MEDLINE Link].

8. Faergemann J, Fredriksson T, Nathorst-Windahl G. One case of confluent and reticulate papillomatosis (Gougerot-Carteaud). Acta Derm Venereol. 1980. 60(3):269-71. [QxMD MEDLINE Link].

9. Broberg A, Faergemann J. A case of confluent and reticulate papillomatosis (Gougerot-Carteaud) with an unusual location. Acta Derm Venereol. 1988. 68(2):158-60. [QxMD MEDLINE Link].

10. Lee D, Cho KJ, Hong SK, Seo JK, Hwang SW, Sung HS. Two cases of confluent and reticulated papillomatosis with an unusual location. Acta Derm Venereol. 2009. 89(1):84-5. [QxMD MEDLINE Link].

11. Kim BS, Lim HJ, Kim HY, et al. Case of minocycline-effective confluent and reticulated papillomatosis with unusual location on forehead. J Dermatol. 2009 Apr. 36(4):251-3. [QxMD MEDLINE Link].

12. Fung MA, Frieden IJ, LeBoit PE, et al. Confluent and reticulate papillomatosis: successful treatment with minocycline. Arch Dermatol. 1996 Nov. 132(11):1400-1. [QxMD MEDLINE Link].

13. Montemarano AD, Hengge M, Sau P, Welch M. Confluent and reticulated papillomatosis: response to minocycline. J Am Acad Dermatol. 1996 Feb. 34(2 Pt 1):253-6. [QxMD MEDLINE Link].

14. Poskitt L, Wilkinson JD. Clearance of confluent and reticulate papillomatosis of Gougerot and Carteaud with minocycline. Br J Dermatol. 1993 Sep. 129(3):351-3. [QxMD MEDLINE Link].

15. Sassolas B, Plantin P, Guillet G. Confluent and reticulated papillomatosis: treatment with minocycline. J Am Acad Dermatol. 1992 Mar. 26(3 Pt 2):501-2. [QxMD MEDLINE Link].

16. Yamamoto A, Okubo Y, Oshima H, Oh-i T, Koga M. Two cases of confluent and reticulate papillomatosis: successful treatments of one case with cefdinir and another with minocycline. J Dermatol. 2000 Sep. 27(9):598-603. [QxMD MEDLINE Link].

17. Rodriguez-Carreon AA, Arenas-Guzman R, Fonte-Avalos V, Gutierrez-Mendoza D, Vega-Memije ME, Dominguez-Cherit J. [Confluent and reticulated Gougerot-Carteaud papillomatosis: a case report of an excellent response to minocycline]. Gac Med Mex. 2008 Jan-Feb. 144(1):67-70. [QxMD MEDLINE Link].

18. Lee SW, Loo CH, Tan WC. Confluent and reticulated papillomatosis: Case series of 3 patients from Kedah, Malaysia and literature review. Med J Malaysia. 2018 Oct. 73 (5):338-339. [QxMD MEDLINE Link].

19. Kägi MK, Trüeb R, Wüthrich B, Burg G. Confluent and reticulated papillomatosis associated with atopy. Successful treatment with topical urea and tretinoin. Br J Dermatol. 1996 Feb. 134(2):381-2. [QxMD MEDLINE Link].

20. Hodge JA, Ray MC. Confluent and reticulated papillomatosis: response to isotretinoin. J Am Acad Dermatol. 1991 Apr. 24(4):654. [QxMD MEDLINE Link].

21. Lee MP, Stiller MJ, McClain SA, Shupack JL, Cohen DE. Confluent and reticulated papillomatosis: response to high-dose oral isotretinoin therapy and reassessment of epidemiologic data. J Am Acad Dermatol. 1994 Aug. 31(2 Pt 2):327-31. [QxMD MEDLINE Link].

22. Schwartzberg JB, Schwartzberg HA. Response of confluent and reticulate papillomatosis of Gougerot and Carteaud to topical tretinoin. Cutis. 2000 Oct. 66(4):291-3. [QxMD MEDLINE Link].

23. Solomon BA, Laude TA. Two patients with confluent and reticulated papillomatosis: response to oral isotretinoin and 10% lactic acid lotion. J Am Acad Dermatol. 1996 Oct. 35(4):645-6. [QxMD MEDLINE Link].

24. Angeli-Besson C, Koeppel MC, Jacquet P, Andrac L, Sayag J. Confluent and reticulated papillomatosis (Gougerot-Carteaud) treated with tetracyclines. Int J Dermatol. 1995 Aug. 34(8):567-9. [QxMD MEDLINE Link].

25. Atasoy M, Ozdemir S, Aktas A, Aliagaoglu C, Karakuzu A, Erdem T. Treatment of confluent and reticulated papillomatosis with azithromycin. J Dermatol. 2004 Aug. 31(8):682-6. [QxMD MEDLINE Link].

26. Carteaud A. [A case of Gougerot and Carteaud's confluent and reticulated papulous papillomatosis, completely cleared up by antibiotics]. Bull Soc Fr Dermatol Syphiligr. 1965 Jul-Aug. 72(4):396-7. [QxMD MEDLINE Link].

27. Gruber F, Zamolo G, Saftic M, Peharda V, Kastelan M. Treatment of confluent and reticulated papillomatosis with azithromycin. Clin Exp Dermatol. 1998 Jul. 23(4):191. [QxMD MEDLINE Link].

28. Jang HS, Oh CK, Cha JH, Cho SH, Kwon KS. Six cases of confluent and reticulated papillomatosis alleviated by various antibiotics. J Am Acad Dermatol. 2001 Apr. 44(4):652-5. [QxMD MEDLINE Link].

29. Raja Babu KK, Snehal S, Sudha Vani D. Confluent and reticulate papillomatosis: successful treatment with azithromycin. Br J Dermatol. 2000 Jun. 142(6):1252-3. [QxMD MEDLINE Link].

30. Weigl LB, Beham A, Schnopp C, Möhrenschlager M, Abeck D. [Confluent and reticulate papillomatosis. Successful therapy with azithromycin]. Hautarzt. 2001 Oct. 52(10 Pt 2):947-9. [QxMD MEDLINE Link].

31. Davis RF, Harman KE. Confluent and reticulated papillomatosis successfully treated with amoxicillin. Br J Dermatol. 2007 Mar. 156(3):583-4. [QxMD MEDLINE Link].

32. Bayramgurler D, Apaydin R, Bilen N. Confluent and reticulate papillomatosis: response to topical calcipotriol. J Dermatolog Treat. 2000. 11:109-11.

33. Carrozzo AM, Gatti S, Ferranti G, Primavera G, Vidolin AP, Nini G. Calcipotriol treatment of confluent and reticulated papillomatosis (Gougerot-Carteaud syndrome). J Eur Acad Dermatol Venereol. 2000 Mar. 14(2):131-3. [QxMD MEDLINE Link].

34. Gulec AT, Seckin D. Confluent and reticulated papillomatosis: treatment with topical calcipotriol. Br J Dermatol. 1999 Dec. 141(6):1150-1. [QxMD MEDLINE Link].

35. Kurkcuoglu N, Celebi CR. Confluent and reticulated papillomatosis: response to topical calcipotriol. Dermatology. 1995. 191(4):341-2. [QxMD MEDLINE Link].

36. Gonul M, Cakmak SK, Soylu S, Kilic A, Gul U, Ergul G. Successful treatment of confluent and reticulated papillomatosis with topical mupirocin. J Eur Acad Dermatol Venereol. 2008 Sep. 22(9):1140-2. [QxMD MEDLINE Link].

37. Bowman PH, Davis LS. Confluent and reticulated papillomatosis: response to tazarotene. J Am Acad Dermatol. 2003 May. 48(5 Suppl):S80-1. [QxMD MEDLINE Link].

38. Berk DR. Confluent and reticulated papillomatosis response to 70% alcohol swabbing. Arch Dermatol. 2011 Feb. 147(2):247-8. [QxMD MEDLINE Link].

39. Gougerot H, Carteaud A. Papillomatose pigmentee inominee. Bull Soc Fr Dermatol Syphiligr. 1927. 34:719-21.

40. Gougerot H, Carteaud A. Papillomatose pigmentee confluente et reticulee innominee. Bull Soc Fr Dermatol Syphiligr. 1928. 35:230-1.

41. Gougerot H, Carteaud A. Neue formen der papillomatose. Arch Dermat Syph. 1932. 165:232-67.

42. Wise F, Sachs, W. Cutaneous papillomatose: papillomatose confluente et reticulee. Arch Dermatol Syphil. 1937. 36:475-85.

43. Wise F. Confluent and reticular papillomatosis (Gougerot-Carteaud). Arch Dermatol Syhphil. 1937. 35:550.

44. Fite LP, Cohen PR. Polycystic Ovarian Syndrome-associated Confluent and Reticulated Papillomatosis: Report of a Patient Successfully Treated with Azithromycin. J Clin Aesthet Dermatol. 2017 Sep. 10 (9):30-35. [QxMD MEDLINE Link].

45. Kanitakis J, Zambruno G, Viac J, Thivolet J. Involucrin expression in keratinization disorders of the skin--a preliminary study. Br J Dermatol. 1987 Oct. 117(4):479-86. [QxMD MEDLINE Link].

46. Tamraz H, Raffoul M, Kurban M, Kibbi AG, Abbas O. Confluent and reticulated papillomatosis: clinical and histopathological study of 10 cases from Lebanon. J Eur Acad Dermatol Venereol. 2011 Nov 3. [QxMD MEDLINE Link].

47. Baden HP. Familial cutaneous papillomatosis. Arch Dermatol. 1965 Oct. 92(4):394-5. [QxMD MEDLINE Link].

48. Henning JP, de Wit RF. Familial occurrence of confluent and reticulated papillomatosis. Arch Dermatol. 1981 Dec. 117(12):809-10. [QxMD MEDLINE Link].

49. Inalöz HS, Patel G, Knight AG. Familial confluent and reticulated papillomatosis: a further clue to the pathogenesis. Br J Dermatol. 1999. 11(Suppl 55):66.

50. Inalöz HS, Patel GK, Knight AG. Familial confluent and reticulated papillomatosis. Arch Dermatol. 2002 Feb. 138(2):276-7. [QxMD MEDLINE Link].

51. Groh V, Schnyder UW, Sigg C. Papillomatose papuleuse confluente et réticulée Gougerot-Carteaud'--a further form of skin amyloidosis?. Dermatologica. 1981. 162(2):118-23. [QxMD MEDLINE Link].

52. Krishnamoorthy M, Nadler E, Vaidya S. Resolution of confluent and reticulated papillomatosis after bariatric surgery. Clin Obes. 2021 Feb. 11 (1):e12427. [QxMD MEDLINE Link].

53. Zhang CH, Zhang C, Wu J, et al. Confluent and reticulated papillomatosis associated with hyperthyroidism. Eur J Dermatol. 2010 Nov-Dec. 20(6):833-5. [QxMD MEDLINE Link].

54. Vassileva S, Pramatarov K, Popova L. Ultraviolet light-induced confluent and reticulated papillomatosis. J Am Acad Dermatol. 1989 Aug. 21(2 Pt 2):413-4. [QxMD MEDLINE Link].

55. Ballout RA, Helou G, Maatouk I. Antiretroviral-responsive confluent and reticulated papillomatosis: a case report of an unusual association. Oxf Med Case Reports. 2019 Oct. 2019 (10):omz099. [QxMD MEDLINE Link].

56. Natarajan S, Milne D, Jones AL, Goodfellow M, Perry J, Koerner RJ. Dietzia strain X: a newly described Actinomycete isolated from confluent and reticulated papillomatosis. Br J Dermatol. 2005 Oct. 153(4):825-7. [QxMD MEDLINE Link].

57. Tamraz H, Raffoul M, Kurban M, Kibbi AG, Abbas O. Confluent and reticulated papillomatosis: clinical and histopathological study of 10 cases from Lebanon. J Eur Acad Dermatol Venereol. 2013 Jan. 27(1):e119-23. [QxMD MEDLINE Link].

58. Jo S, Park HS, Cho S, Yoon HS. Updated diagnosis criteria for confluent and reticulated papillomatosis: a case report. Ann Dermatol. 2014 Jun. 26(3):409-10. [QxMD MEDLINE Link]. [Full Text].

59. Sakiyama T, Amagai M, Ohyama M. Chronology of confluent and reticulated papillomatosis: spontaneous regression in a case after long-term follow-up may imply transient nature of the condition. J Dermatol. 2015 Mar. 42 (3):335-6. [QxMD MEDLINE Link].

60. Cordero A. [Confluent and reticular papulous Gougerot and Carteaoud's papillomatosis or acanthosis nigricans.]. Soc Ital Dermatol Sifilogr Sezioni Interprov Soc Ital Dermatol Sifilogr. 1952 Nov-Dec. 93(6):500-9. [QxMD MEDLINE Link].

61. Degos R, Ossipowski B. [Reticulated pigmentary dermatosis of the folds: relation to acanthosis nigricans.]. Ann Dermatol Syphiligr (Paris). 1954 Mar-Apr. 81(2):147-51. [QxMD MEDLINE Link].

62. Fukumoto T, Kozaru T, Sakaguchi M, Oka M. Concomitant confluent and reticulated papillomatosis and acanthosis nigricans in an obese girl with insulin resistance successfully treated with oral minocycline: Case report and published work review. J Dermatol. 2017 Mar 11. [QxMD MEDLINE Link].

63. Ahogo KC, Gbery PI, Bamba V, Kouassi YI, Ecra EJ, Kouassi KA, et al. Confluent and Reticulated Papillomatosis of Gougerot-Carteaud on Black Skin: Two Observations. Case Rep Dermatol Med. 2016. 2016:2507542. [QxMD MEDLINE Link].

64. Shevchenko A, Valdes-Rodriguez R, Hsu S, Motaparthi K. Prurigo pigmentosa: Case series and differentiation from confluent and reticulated papillomatosis. JAAD Case Rep. 2018 Jan. 4 (1):77-80. [QxMD MEDLINE Link].

65. Jimbow M, Talpash O, Jimbow K. Confluent and reticulated papillomatosis: clinical, light and electron microscopic studies. Int J Dermatol. 1992 Jul. 31(7):480-3. [QxMD MEDLINE Link].

66. Ferreira LM, Diniz LM, Ferreira CJ. [Confluent and reticulated papillomatosis of Gougerot and Carteaud: report of three cases]. An Bras Dermatol. 2009 Jan-Feb. 84(1):78-81. [QxMD MEDLINE Link].

67. Rao TN, Guruprasad P, Sowjanya ChL, Nagasridevi I. Confluent and reticulated papillomatosis: successful treatment with minocycline. Indian J Dermatol Venereol Leprol. 2010 Nov-Dec. 76(6):725. [QxMD MEDLINE Link].

68. Erkek E, Ayva S, Atasoy P, Emeksiz MC. Confluent and reticulated papillomatosis: favourable response to low-dose isotretinoin. J Eur Acad Dermatol Venereol. 2009 Nov. 23(11):1342-3. [QxMD MEDLINE Link].

69. Carlin N, Marcus L, Carlin R. Gougerot-Carteaud Syndrome Treated with 13-cis-retinoic Acid. J Clin Aesthet Dermatol. 2010 Jul. 3(7):56-7. [QxMD MEDLINE Link]. [Full Text].

70. Tirado-Sánchez A, Ponce-Olivera RM. Tacrolimus in confluent and reticulated papillomatosis of Gougerot Carteaud. Int J Dermatol. 2013 Apr. 52(4):513-4. [QxMD MEDLINE Link].

71. Kurtyka DJ, Burke KT, DeKlotz CMC. Use of Topical Sirolimus (Rapamycin) for Treating Confluent and Reticulated Papillomatosis. JAMA Dermatol. 2021 Jan 1. 157 (1):121-123. [QxMD MEDLINE Link].

72. Nordby CA, Mitchell AJ. Confluent and reticulated papillomatosis responsive to selenium sulfide. Int J Dermatol. 1986 Apr. 25(3):194-9. [QxMD MEDLINE Link].

73. Baalbaki SA, Malak JA, al-Khars MA. Confluent and reticulated papillomatosis. Treatment with etretinate. Arch Dermatol. 1993 Aug. 129(8):961-3. [QxMD MEDLINE Link].

74. Bruynzeel-Koomen CA, de Wit RF. Confluent and reticulated papillomatosis successfully treated with the aromatic etretinate. Arch Dermatol. 1984 Sep. 120(9):1236-7. [QxMD MEDLINE Link].

75. Ginarte M, Fabeiro JM, Toribio J. Confluent and reticulated papillomatosis (Gougerot-Carteaud) successfully treated with tacalcitol. J Dermatolog Treat. 2002 Mar. 13(1):27-30. [QxMD MEDLINE Link].

76. Nunes de Mattos AB, Brummer CF, Funchal GDG, Nunes DH. Use of methotrexate in an exuberant case of confluent and reticulated papillomatosis of Gougerot and Carteaud in a teenager. An Bras Dermatol. 2019 Nov - Dec. 94 (6):717-720. [QxMD MEDLINE Link].

Robert A Schwartz, MD, MPH Professor and Head of Dermatology, Professor of Pathology, Professor of Pediatrics, Professor of Medicine, Rutgers New Jersey Medical School

Robert A Schwartz, MD, MPH is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, New York Academy of Medicine, Royal College of Physicians of Edinburgh, Sigma Xi, The Scientific Research Honor Society

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

William D James, MD Paul R Gross Professor of Dermatology, Vice-Chairman, Residency Program Director, Department of Dermatology, University of Pennsylvania School of Medicine

William D James, MD is a member of the following medical societies: American Academy of Dermatology, Society for Investigative Dermatology

Disclosure: Received income in an amount equal to or greater than $250 from: Elsevier; WebMD<br/>Served as a speaker for various universities, dermatology societies, and dermatology departments.

Ponciano D Cruz, Jr, MD Professor and Vice-Chair, Paul R Bergstresser Chair, Department of Dermatology, University of Texas Southwestern Medical Center

Ponciano D Cruz, Jr, MD is a member of the following medical societies: Texas Medical Association

Disclosure: Received consulting fee from RCTS for independent contractor; Received honoraria from Mary Kay Cosmetics for consulting; Received grant/research funds from Galderma for principal investigator.

The authors and editors of Medscape Reference gratefully acknowledge the contributions of previous author, Kenneth A. Becker, MD, to the development and writing of this article.

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