Keratosis Follicularis (Darier Disease) Questions & Answers

Updated: Jul 31, 2018
  • Author: Pui-Yan Kwok, MD, PhD; Chief Editor: Dirk M Elston, MD  more...
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Questions & Answers

Overview

What keratosis follicularis (Darier disease)?

What is the pathophysiology of keratosis follicularis (Darier disease)?

What is the role of calcium regulation in the pathophysiology of keratosis follicularis (Darier disease)?

What is the prevalence of keratosis follicularis (Darier disease)?

What are the sexual predilections of keratosis follicularis (Darier disease)?

Which age groups have the highest prevalence of keratosis follicularis (Darier disease)?

What is the prognosis of keratosis follicularis (Darier disease)?

Presentation

Which clinical history findings are characteristic of keratosis follicularis (Darier disease)?

Which physical findings are characteristic of keratosis follicularis (Darier disease)?

What are the possible complications of keratosis follicularis (Darier disease)?

DDX

Which conditions should be included in the differential diagnoses of keratosis follicularis (Darier disease)?

What are the differential diagnoses for Keratosis Follicularis (Darier Disease)?

Workup

How is a diagnosis of keratosis follicularis (Darier disease) confirmed?

What is the role of biopsy in the diagnosis of keratosis follicularis (Darier disease)?

Which histologic findings are characteristic of keratosis follicularis (Darier disease)?

Treatment

How is keratosis follicularis (Darier disease) treated?

What is the role of topical medications in the treatment of keratosis follicularis (Darier disease)?

What is the role of botulinum toxin type A in the treatment of keratosis follicularis (Darier disease)?

What is the role of oral medications in the treatment of keratosis follicularis (Darier disease)?

What is the role of surgery in the treatment of keratosis follicularis (Darier disease)?

Medications

What is the goal of drug treatment for keratosis follicularis (Darier disease)?

Which medications in the drug class Retinoid-like Agents are used in the treatment of Keratosis Follicularis (Darier Disease)?