CHILD Syndrome Medication

Updated: Aug 20, 2019
  • Author: Amanda T Moon, MD; Chief Editor: Dirk M Elston, MD  more...
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Medication

Medication Summary

Cutaneous findings are treated with systemic or topical steroids. Keratolytics have also been advocated.

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Keratolytics

Class Summary

These agents are used for symptomatic relief of dry, scaling skin. They also help exfoliate the skin.

Ammonium lactate (Lac-Hydrin, AmLactin)

Ammonium lactate relieves itching and aids healing of skin in persons with mild eczemas and dermatoses, minor wounds, and minor skin irritations. Lactic acid is an alpha-hydroxy acid.

Urea (Ureacin, Ureaphil, Carmol) creams or lotions

Urea is used topically in the treatment of dry skin. It promotes hydration and removal of excess keratin in conditions of hyperkeratosis. At concentrations of 10-40%, it has a keratolytic effect.

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Retinoids

Class Summary

Topical and systemic retinoids have been advocated to help normalize the keratinization of the epidermis.

Tretinoin topical (Retin-A, Avita, Renova)

Tretinoin topical normalizes keratinization.

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