Erythema Toxicum Neonatorum Treatment & Management

Updated: Oct 05, 2020
  • Author: Neil F Gibbs, MD; Chief Editor: William D James, MD  more...
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Medical Care

Erythema toxicum neonatorum (ETN) diagnosis rests on recognizing the characteristic history and physical findings in an otherwise healthy newborn.

A complete history, physical examination, and Tzanck smear are required to differentiate between benign transient pustular eruptions of the newborn and life-threatening disease.

Erythema toxicum neonatorum is a benign self-limited disorder requiring no treatment. Reassure parents regarding the benign transitory nature of the condition. [29]


Long-Term Monitoring

Most erythema toxicum neonatorum (ETN) cases resolve within 3-4 days after onset without residua. Rare recurrences are seen in a small number of patients up to age 6 weeks. In these instances, follow-up examination may be needed.