Piebaldism Workup

Updated: Apr 06, 2021
  • Author: Camila K Janniger, MD; Chief Editor: Dirk M Elston, MD  more...
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Workup

Approach Considerations

Targeted next-generation sequencing can be effectively used for molecular diagnosis. [30]

Regarding histology findings, poliosis has either decreased or absent melanin and/or melanocytes in the hair bulbs of the affected hair follicles, which can be confirmed using special stains for melanin or melanocytes. [28] The epidermal melanocytes are usually unaffected unless there is also vitiligo.