Ehlers-Danlos Syndrome Differential Diagnoses

Updated: Feb 23, 2021
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
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DDx

Diagnostic Considerations

Also consider the following:

  • Muscular hypotonia (kyphoscoliotic type)

  • Loeys-Dietz syndrome [42]

  • Child abuse: Ehlers-Danlos syndrome may resemble child abuse in some patients, a potential medicolegal concern and challenge. [43]

  • Systemic connective-tissue disorder with polyvalvular heart; generalized joint hypermobility and related musculoskeletal complications; soft, velvety, and hyperextensible skin; short limbs; hearing impairment; and facial dysmorphism associated with TAB2 mutations [44]

Differential Diagnoses