Ehlers-Danlos Syndrome Differential Diagnoses

Updated: Mar 17, 2020
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
  • Print

Diagnostic Considerations

Also consider the following:

  • Muscular hypotonia (kyphoscoliotic type)

  • Loeys-Dietz syndrome [40]

  • Child abuse: Ehlers-Danlos syndrome may resemble child abuse in some patients, a potential medicolegal concern and challenge. [41]

  • Systemic connective-tissue disorder with polyvalvular heart; generalized joint hypermobility and related musculoskeletal complications; soft, velvety, and hyperextensible skin; short limbs; hearing impairment; and facial dysmorphism associated with TAB2 mutations [42]

Differential Diagnoses