Werner Syndrome Treatment & Management

Updated: Jun 05, 2017
  • Author: Camila K Janniger, MD; Chief Editor: Dirk M Elston, MD  more...
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Medical Care

Specific treatment for Werner syndrome (WS) does not exist. Only symptomatic treatment of related disturbances is recommended. Results of a 2010 study on mice suggest that vitamin C supplementation could be beneficial for patients with WS. [20]



Consultations are related to the concomitant diseases.



Complications of Werner syndrome (WS) are related to the concomitant diseases and symptoms described above (see Physical Examination). Pregnancy complicated by the presence of Werner syndrome has been reported. [21]

The variant genotype of WRN Leu1074Phe has been associated with a 1.36-fold significantly increased risk of breast cancer in Chinese women, particularly pronounced in those carrying Phe/Phe genotype and having an earlier age at menarche, to produce a 3.58-fold increased risk of breast cancer. [22]

Patients with WS may develop severe cystoid macular edema after laser therapy. [23]