Dermatologic Manifestations of Homocystinuria Medication

Updated: Jun 21, 2018
  • Author: Janette Baloghova, MD, PhD; Chief Editor: Dirk M Elston, MD  more...
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Medication Summary

The goals of pharmacotherapy are to reduce morbidity and to prevent complications.


Dietary supplements

Class Summary

These agents are used to correct nutritional deficiencies. In addition to the supplements listed below, cysteine is a sulfur-containing amino acid. It is generally considered an essential amino acid in infants.

Betaine anhydrous (Cystadane)

Betaine anhydrous is an antihomocystinuric that acts as a methyl-group donor in the remethylation of homocysteine to methionine, removing excess homocysteine from the body.



Class Summary

Vitamins are essential for normal DNA synthesis.

Pyridoxine (Pyri 500, Neuro-K)

Pyridoxine is a precursor to pyridoxal, which is important in the metabolism of proteins, carbohydrates, and fats. It also aids in the release of liver- and muscle-stored glycogen. It is involved in the synthesis of GABA in the CNS.

Cyanocobalamin (Pysicians EZ use B-12, B-12 Compliance injection)

Cyanocobalamin deoxyadenosylcobalamin and hydroxocobalamin are active forms of vitamin B-12 in humans. Vitamin B-12 is synthesized by microbes but not by humans or plants. It is a coenzyme in various metabolic functions, including carbohydrate and fat metabolism and protein synthesis, which are responsible for cell replication and hematopoiesis.

Folic acid (FA-8)

Folic acid is an important cofactor for enzymes used in nucleoprotein synthesis and maintenance of erythropoiesis. It stimulates white blood cells and platelet production in folate deficiency anemia.