Cockayne Syndrome Treatment & Management

Updated: Jun 25, 2018
  • Author: Suguru Imaeda, MD; Chief Editor: William D James, MD  more...
  • Print

Medical Care

Medical care for Cockayne syndrome patients includes photoprotection with sunscreens and clothing.

Studies showing hepatic toxicity associated with metronidazole use suggests that metronidazole is contraindicated in patients with Cockayne syndrome. [21]


Surgical Care

Cochlear implantation can help minimize the effects of auditory impairment. [22, 23]

Perioperative management of Cockayne syndrome patients requires special consideration of the characteristic growth arrest, with failure to grow coupled with accelerated aging. Weight-appropriate rather than age-appropriate airway equipment is necessary for airway management. [24] Depending on the severity of the Cockayne syndrome, it may not be uncommon to encounter adult diseases, such as myocardial ischemia, [25] renal impairment, and diabetes mellitus, even in early childhood. [26]



Consult the following specialists for Cockayne syndrome patients:

  • Neurologist for neurologic deterioration, ataxia, and deafness

  • Ear, nose, and throat specialist for sensorineural deafness

  • Ophthalmologist for optic atrophy and cataracts

  • Dentist for caries

  • Geneticist for prenatal evaluation and genetic counseling