Dermatopathia Pigmentosa Reticularis Workup

Updated: Nov 22, 2019
  • Author: Melba Estrella, MD; Chief Editor: Dirk M Elston, MD  more...
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Workup

Laboratory Studies

Dermatopathia pigmentosa reticularis (DPR) does not warrant laboratory studies beyond genetic testing because of the lack of consistent report of abnormal results.

Al-Hamdi [21] et al reported an isolated case of DPR with elevated serum cortisol and hepatomegaly.

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Procedures

Excisional or punch cutaneous biopsy of the reticular pigmentation may be helpful when making the diagnosis of dermatopathia pigmentosa reticularis (DPR).

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Histologic Findings

The typical histopathologic picture of dermatopathia pigmentosa reticularis (DPR) shows hyperpigmentation of the basal layer with cytoplasmic vacuolization and the presence of melanophages within the reticular dermis. [2, 21] That is, an interface dermatitis can be present.

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