Hydroa Vacciniforme Treatment & Management

Updated: Aug 05, 2019
  • Author: Gregory Toy; Chief Editor: Dirk M Elston, MD  more...
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Treatment

Medical Care

In addition to medication and certain restrictions on activity, management of hydroa vacciniforme (HV) may include a prophylactic "hardening" course of phototherapy. In a study of four patients with HV, low-dose, narrow-band UV-B (TL-01) phototherapy, either daily or 3 times a week in the spring, was shown to confer relative photoprotection. [30] Psoralen photochemotherapy (PUVA) administered prophylactically in older patients may be effective in desensitization. After intercalating with DNA and irradiation by UV-A, methoxsalen leads to formation of DNA psoralen adducts that cross-link DNA. [31]

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Consultations

Consult a dermatologist for evaluation and management of hydroa vacciniforme (HV). 

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Diet

Generally, no diet restrictions or requirements are indicated in the management of hydroa vacciniforme (HV).

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Activity

Strict sun avoidance, appropriate clothing, and frequent application of high sun protection factor (SPF) sunscreens with UV-A blocking agents are advised.

Rigid sun avoidance may be socially devastating for the pediatric patient with hydroa vacciniforme (HV). The physician should work closely with the parents and management team in supporting and educating the child regarding this disease.

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Prevention

Avoiding the sun, frequently applying high SPF sunscreens with UV-A blocking agents, and wearing protective clothing may prevent episodes of hydroa vacciniforme (HV).

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Long-Term Monitoring

Patients with extracutaneous findings associated with hydroa vacciniforme (HV) should be referred to the appropriate specialist.

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