Diagnostic Considerations

Other considerations include the following:

Fixed drug eruption
Erosive lichen planus ^{[17, 18]}
Erosive balanitis
Solitary plasmocytoma
Malignant plasma cell tumors in HIV-infected patients ^[19]
Syphilis: In 2007, Babu et al noted primary syphilis presenting as balanitis. ^[20]Others have also noted primary syphilis being on the differential diagnosis of balanitis circumscripta plasmacellularis. ^[21]

Differential Diagnoses

Workup

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Pearce J, Fernando I. The value of a multi-specialty service, including genitourinary medicine, dermatology and urology input, in the management of male genital dermatoses. Int J STD AIDS. 2015 Sep. 26 (10):716-22. [QxMD MEDLINE Link].
Adégbidi H, Atadokpèdé F, Dégboé B, Saka B, Akpadjan F, Yédomon H, et al. Zoon's balanitis in circumcised and HIV infected man, at Cotonou (Benin). Bull Soc Pathol Exot. 2014 Aug;. 107(3):139-41. [QxMD MEDLINE Link].
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Houser ER, Gaston KE, Funkhouser WK, Israel B, Lavelle JP. Plasma cell (Zoon's) balanitis with concomitant HIV infection. Urology. 2005 Sep. 66(3):657. [QxMD MEDLINE Link].
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Vartolomei MD, Cotoi OS, Badea MA, Chibelean CB, Cotoi T, Morariu V, et al. Indurative Edema of the Prepuce Mimicing Phimosis, an Atypical Manifestation of Primary Syphilis. Acta Dermatovenerol Croat. 2015 Dec. 23 (4):301-3. [QxMD MEDLINE Link].
Arzberger E, Komericki P, Ahlgrimm-Siess V, Massone C, Chubisov D, Hofmann-Wellenhof R. Differentiation Between Balanitis and Carcinoma In Situ Using Reflectance Confocal Microscopy. JAMA Dermatol. 2013 Jan 16. 1-6. [QxMD MEDLINE Link].
Errichetti E, Lacarrubba F, Micali G, Stinco G. Dermoscopy of Zoon's plasma cell balanitis. J Eur Acad Dermatol Venereol. 2016 Dec. 30 (12):e209-e210. [QxMD MEDLINE Link].
Alessi E, Coggi A, Gianotti R. Review of 120 biopsies performed on the balanopreputial sac. from zoon's balanitis to the concept of a wider spectrum of inflammatory non-cicatricial balanoposthitis. Dermatology. 2004. 208(2):120-4. [QxMD MEDLINE Link].
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Media Gallery

Plasmacytosis mucosae of balanitis circumscripta plasmacellularis (plasma cell balanitis or Zoon balanitis. Hematoxylin and eosin stain. Courtesy of Nephron, via Wikimedia Commons.

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Author

Elizabeth U Rogozinski, MD, MS Medical and Cosmetic Dermatologist, Center for Dermatology and Plastic Surgery

Elizabeth U Rogozinski, MD, MS is a member of the following medical societies: American Academy of Dermatology, American Medical Association, Medical Dermatology Society

Disclosure: Nothing to disclose.

Coauthor(s)

Julian J Trevino, MD Professor and Chair of Dermatology, Dermatology Residency Program Director, Wright State University, Boonshoft School of Medicine; Chief, Division of Pediatric Dermatology, Dayton Children’s Hospital

Julian J Trevino, MD is a member of the following medical societies: American Academy of Dermatology, American Medical Association, Ohio Dermatological Association, Ohio State Medical Association

Disclosure: Nothing to disclose.

Specialty Editor Board

Richard P Vinson, MD Assistant Clinical Professor, Department of Dermatology, Texas Tech University Health Sciences Center, Paul L Foster School of Medicine; Consulting Staff, Mountain View Dermatology, PA

Richard P Vinson, MD is a member of the following medical societies: American Academy of Dermatology, Texas Medical Association, Association of Military Dermatologists, Texas Dermatological Society

Disclosure: Nothing to disclose.

Rosalie Elenitsas, MD Herman Beerman Professor of Dermatology, University of Pennsylvania School of Medicine; Director, Penn Cutaneous Pathology Services, Department of Dermatology, University of Pennsylvania Health System

Rosalie Elenitsas, MD is a member of the following medical societies: American Academy of Dermatology, American Medical Association, American Society of Dermatopathology, Pennsylvania Academy of Dermatology

Disclosure: Received royalty from Lippincott Williams Wilkins for textbook editor.

Chief Editor

Dirk M Elston, MD Professor and Chairman, Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina College of Medicine

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Additional Contributors

Janet Fairley, MD Professor and Head, Department of Dermatology, University of Iowa, Roy J and Lucille A Carver College of Medicine

Janet Fairley, MD is a member of the following medical societies: American Academy of Dermatology, American Federation for Medical Research, Society for Investigative Dermatology

Disclosure: Nothing to disclose.

Noah S Scheinfeld, JD, MD, FAAD † Assistant Clinical Professor, Department of Dermatology, Weil Cornell Medical College; Consulting Staff, Department of Dermatology, St Luke's Roosevelt Hospital Center, Beth Israel Medical Center, New York Eye and Ear Infirmary; Assistant Attending Dermatologist, New York Presbyterian Hospital; Assistant Attending Dermatologist, Lenox Hill Hospital, North Shore-LIJ Health System; Private Practice

Noah S Scheinfeld, JD, MD, FAAD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Acknowledgements

George C Keough, MD Chief, Clinical Assistant Professor, Department of Medicine, Dermatology Service, Eisenhower Army Medical Center

George C Keough, MD is a member of the following medical societies: American Academy of Dermatology and American Medical Association

Disclosure: Nothing to disclose.

Daniel S Lehman, MD Fellow in Minimally Invasive Urology/Oncology, Department of Urology, Columbia University Medical Center

Disclosure: Nothing to disclose.