Dermatologic Aspects of Behcet Disease Differential Diagnoses

Updated: May 13, 2019
  • Author: Amira M Elbendary, MD, MBBCh, MSc; Chief Editor: William D James, MD  more...
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Diagnostic Considerations

Crohn disease has overlapping features with Behçet disease, namely gastrointestinal, cutaneous, articular, ocular, and cardiac manifestations. [121] The combination of arterial aneurysms and venous thrombosis should raise the suspicion of a diagnosis of Behçet disease. Finding a single or a few, large, discrete, and round or oval ulcerations in the ileocecal area also suggests Behçet disease. In Crohn disease, longitudinal ulcers (defined as ≥4-5 cm) in a discontinuous distribution, cobblestone appearance, and/or small aphthous ulcerations arranged in a longitudinal fashion are usually found. Histologic findings also help in distinguishing both entities.

Differential Diagnoses