Dyshidrotic Eczema (Pompholyx) Questions & Answers

Updated: Apr 22, 2020
  • Author: Sadegh Amini, MD; Chief Editor: William D James, MD  more...
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Questions & Answers

Overview

What is the typical presentation and clinical course of dyshidrotic eczema (pompholyx)?

Which clinical history findings are characteristic of dyshidrotic eczema (pompholyx)?

What is the role of lab tests in the workup for dyshidrotic eczema (pompholyx)?

How is dyshidrotic eczema (pompholyx) treated?

What is dyshidrotic eczema (dyshidrosis) (pompholyx) and what is its clinical presentation and course?

What new term has been proposed to replace dyshidrotic eczema (dyshidrosis) (pompholyx)?

What is the etiology of dyshidrotic eczema (dyshidrosis) (pompholyx)?

Is atopy a possible etiologic factor in dyshidrotic eczema (dyshidrosis) (pompholyx)?

Which exogenous factors may trigger episodes of dyshidrotic eczema (dyshidrosis) (pompholyx)?

Which environmental factors may exacerbate dyshidrotic eczema (dyshidrosis) (pompholyx)?

Is dyshidrotic eczema (dyshidrosis) (pompholyx) an adverse effect of IVIG infusions?

Can tinea pedis (athlete’s foot) cause dyshidrotic eczema (dyshidrosis) (pompholyx)?

Is dyshidrotic eczema (dyshidrosis) (pompholyx) a genetic disorder?

Which mutations contribute to the genetic factors of dyshidrotic eczema (dyshidrosis) (pompholyx)?

What is the role of aquaporins in the pathogenesis of dyshidrotic eczema (dyshidrosis) (pompholyx)?

What is the prevalence of atopy in patients with dyshidrotic eczema (dyshidrosis) (pompholyx)?

What is the role of nickel sensitivity in the etiology of dyshidrotic eczema (dyshidrosis) (pompholyx)?

Is cobalt sensitivity a significant etiologic factor in dyshidrotic eczema (dyshidrosis) (pompholyx)?

Which sensitizing chemical and metal exposures can cause dyshidrotic eczema (dyshidrosis) (pompholyx)?

Is an id reaction possible in patients with dyshidrotic eczema (dyshidrosis) (pompholyx)?

What is the role of fungal infection in the etiology of dyshidrotic eczema (dyshidrosis) (pompholyx)?

Is emotional stress an etiologic factor in dyshidrotic eczema (dyshidrosis) (pompholyx)?

What are less common causative factors of dyshidrotic eczema (dyshidrosis) (pompholyx)?

What is the role of ultraviolet A (UVA) light in the etiology of dyshidrotic eczema (dyshidrosis) (pompholyx)?

What are the treatment options for dyshidrotic eczema (dyshidrosis) (pompholyx) caused by ultraviolet A (UVA) light?

What is the prevalence of dyshidrotic eczema (dyshidrosis) (pompholyx) in the US?

What is the global prevalence of dyshidrotic eczema (dyshidrosis) (pompholyx)?

Does the prevalence of dyshidrotic eczema (dyshidrosis) (pompholyx) vary between males and females or among age groups?

What is the prognosis of dyshidrotic eczema (dyshidrosis) (pompholyx)?

What education should be given to patients with dyshidrotic eczema (dyshidrosis) (pompholyx)?

Presentation

What are the signs and symptoms of dyshidrotic eczema (dyshidrosis) (pompholyx)?

Which factors may trigger dyshidrotic eczema (dyshidrosis) (pompholyx)?

Is dyshidrotic eczema (dyshidrosis) (pompholyx) a symptom of HIV infection?

Are there treatment algorithms for dyshidrotic eczema (dyshidrosis) (pompholyx)?

What are the physical findings suggestive of dyshidrotic eczema (dyshidrosis) (pompholyx)?

What are the physical findings suggestive of mild dyshidrotic eczema (dyshidrosis) (pompholyx)?

How are vesicles characterized in dyshidrotic eczema (dyshidrosis) (pompholyx)?

Where does dyshidrotic eczema (dyshidrosis) (pompholyx) most commonly occur?

What is the Dyshidrotic Eczema Area and Severity Index?

What are physical findings of long-standing dyshidrotic eczema (dyshidrosis) (pompholyx)?

What are the possible complications of dyshidrotic eczema (dyshidrosis) (pompholyx)?

DDX

What conditions should be included in the differential diagnoses of dyshidrotic eczema (dyshidrosis) (pompholyx)?

What are the differential diagnoses for Dyshidrotic Eczema (Pompholyx)?

Workup

How is dyshidrotic eczema (dyshidrosis) (pompholyx) diagnosed?

What is the role of oral challenge allergy testing in the evaluation of dyshidrotic eczema (dyshidrosis) (pompholyx)?

What is the role of skin patch allergy testing in the evaluation of dyshidrotic eczema (dyshidrosis) (pompholyx)?

What is the role of punch biopsy in the evaluation of dyshidrotic eczema (dyshidrosis) (pompholyx)?

What are the likely histologic findings of dyshidrotic eczema (dyshidrosis) (pompholyx)?

Treatment

What are the first-line and second-line treatments for dyshidrotic eczema (dyshidrosis) (pompholyx)?

Is topical photochemistry an effective treatment for dyshidrotic eczema (dyshidrosis) (pompholyx)?

What are potential treatments under investigation for dyshidrotic eczema (dyshidrosis) (pompholyx)?

What is the role of oxybutynin in the treatment of dyshidrotic eczema (dyshidrosis) (pompholyx)?

What is the role of stress management therapy in the treatment of dyshidrotic eczema (dyshidrosis) (pompholyx)?

What is the treatment for bullae in patients with dyshidrotic eczema (dyshidrosis) (pompholyx)?

When is activity restricted in patients with dyshidrotic eczema (dyshidrosis) (pompholyx)?

Which measures may deter recurrence of dyshidrotic eczema (dyshidrosis) (pompholyx)?

Which specialist consultations may be helpful for patients with dyshidrotic eczema (dyshidrosis) (pompholyx)?

What is the role of ultraviolet A (UVA) light in the treatment for dyshidrotic eczema (dyshidrosis) (pompholyx)?

What is the role of corticosteroids in the treatment of dyshidrotic eczema (dyshidrosis) (pompholyx)?

What is the role of calcineurin inhibitors in the treatment for dyshidrotic eczema (dyshidrosis) (pompholyx)?

What is the role of onabotulinumtoxinA (Botox) injections in the treatment of dyshidrotic eczema (dyshidrosis) (pompholyx)?

Which immunosuppressive agents may be helpful for the treatment of refractory dyshidrotic eczema (dyshidrosis) (pompholyx)?

When are nickel chelators indicated for the treatment of dyshidrotic eczema (dyshidrosis) (pompholyx)?

What is the role of khellin in the treatment of dyshidrotic eczema (dyshidrosis) (pompholyx)?

What is the role of alitretinoin (9-cis retinoic acid) in the treatment of dyshidrotic eczema (dyshidrosis) (pompholyx)?

What is the role of alitretinoin 1% gel in the treatment of dyshidrotic eczema (dyshidrosis) (pompholyx)?

What is the efficacy of oral alitretinoin in the treatment of dyshidrotic eczema (dyshidrosis) (pompholyx)?

What are possible adverse effects of oral alitretinoin in the treatment of dyshidrotic eczema (dyshidrosis) (pompholyx)?

Which potential agents have been shown to be effective for the treatment of dyshidrotic eczema (dyshidrosis) (pompholyx)?

Which diet restrictions are recommended for nickel-sensitive dyshidrotic eczema (dyshidrosis) (pompholyx)?

What diet regimens are recommended for cobalt-sensitive dyshidrotic eczema (dyshidrosis) (pompholyx)?

Medications

What are the challenges of dyshidrotic eczema (dyshidrosis) (pompholyx) treatment?

What is the role of pimecrolimus (Elidel) in the treatment of dyshidrotic eczema (dyshidrosis) (pompholyx)?

What are treatment options for dyshidrotic eczema (dyshidrosis) (pompholyx)?

Which medications in the drug class Corticosteroids are used in the treatment of Dyshidrotic Eczema (Pompholyx)?

Which medications in the drug class Immunosuppressives are used in the treatment of Dyshidrotic Eczema (Pompholyx)?

Which medications in the drug class Antibiotics are used in the treatment of Dyshidrotic Eczema (Pompholyx)?

Which medications in the drug class Antihistamines are used in the treatment of Dyshidrotic Eczema (Pompholyx)?

Which medications in the drug class Nickel Chelators are used in the treatment of Dyshidrotic Eczema (Pompholyx)?