Erythema Annulare Centrifugum Medication

Updated: Sep 05, 2018
  • Author: Marisel Peralta-Abejo, MD, DPDS; Chief Editor: William D James, MD  more...
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Medication

Medication Summary

The goals of pharmacotherapy for erythema annulare centrifugum (EAC) are to reduce morbidity and to prevent complications.

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Corticosteroids

Class Summary

Topical agents are used for treatment of inflammatory lesions of EAC and for symptomatic relief of pruritus. A short course of systemic steroid therapy may be considered for very symptomatic cases of EAC (eg, severe pruritus).

Fluocinonide (Fluonex, Lidex)

Fluocinonide is a group II topical steroid. The anti-inflammatory potency group is determined by the degree of vasoconstriction induced by the drug in the small vessels of the upper dermis (I is most potent; VII is least potent). Use fluocinonide in all involved areas except those where the skin is particularly thin (eg, face, scrotum, axilla, flexural areas).

Hydrocortisone valerate (Westcort)

Hydrocortisone valerate is a group V topical steroid. The anti-inflammatory potency group is determined by the degree of vasoconstriction induced by the drug in the small vessels of the upper dermis (I is most potent; VII is least potent). This topical corticosteroid should be used on involved areas of the skin that are particularly thin, such as the face, axilla, scrotum, and flexural areas.

Prednisone (Deltasone)

Prednisone is an immunosuppressant for the treatment of autoimmune disorders. It may decrease inflammation by reversing increased capillary permeability and suppressing PMN activity. Prednisone stabilizes lysosomal membranes and suppresses lymphocyte and antibody production.

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