Lichen Nitidus Medication

Updated: Nov 20, 2019
  • Author: Zeina Tannous, MD; Chief Editor: William D James, MD  more...
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Class Summary

Corticosteroids have anti-inflammatory properties and cause profound and varied metabolic effects. In addition, these agents modify the body's immune response to diverse stimuli.

Prednisone (Deltasone)

Prednisone may decrease inflammation by reversing increased capillary permeability and suppressing PMN activity.

Methylprednisolone (Solu-Medrol, Depo-Medrol)

Methylprednisolone decreases inflammation by suppressing migration of polymorphonuclear leukocytes and reversing increased capillary permeability.



Class Summary

Antihistamines act by competitive inhibition of histamine at the H1 receptor. They mediate bronchial constriction, mucous secretion, smooth muscle contraction, edema, hypotension, CNS depression, and cardiac arrhythmias.

Cetirizine (Zyrtec)

Cetirizine forms complex with histamine for H1-receptor sites in blood vessels, GI tract, and respiratory tract.



Class Summary

Retinoids have the ability to modulate cell proliferation.

Acitretin (Soriatane)

Acitretin is a retinoic acid analog, like etretinate and isotretinoin. Etretinate is the main metabolite and has demonstrated clinical effects close to those seen with etretinate. Its mechanism of action is unknown.