Lichen Nitidus Workup

Updated: Nov 20, 2019
  • Author: Zeina Tannous, MD; Chief Editor: William D James, MD  more...
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A skin biopsy for histopathologic examination may be obtained to confirm the clinical diagnosis.


Histologic Findings

The papule of lichen nitidus consists of a lymphohistiocytic inflammatory cell infiltrate that lies in close proximity to the epidermis and is associated with basal cell hydropic degeneration. The overlying epidermis is flattened and parakeratotic. At the lateral margins of the papule, the rete ridges extend downward and seem to hug the inflammatory infiltrate, which may be granulomatous.