Polymorphic Eruption of Pregnancy Questions & Answers

1. Lawley TJ, Hertz KC, Wade TR, Ackerman AB, Katz SI. Pruritic urticarial papules and plaques of pregnancy. JAMA. 1979 Apr 20. 241(16):1696-9. [QxMD MEDLINE Link].

2. Chouk C, Litaiem N. Pruritic Urticarial Papules And Plaques Of Pregnancy (PUPPP). StatPearls [Internet]. 2020 Jan. [QxMD MEDLINE Link]. [Full Text].

3. Bourne G. Toxaemic rash of pregnancy. Proc R Soc Med. 1962 Jun. 55:462-4. [QxMD MEDLINE Link].

4. Ambros-Rudolph CM, Mullegger RR, Vaughan-Jones SA, Kerl H, Black MM. The specific dermatoses of pregnancy revisited and reclassified: results of a retrospective two-center study on 505 pregnant patients. J Am Acad Dermatol. 2006 Mar. 54(3):395-404. [QxMD MEDLINE Link].

5. Roth MM. Pregnancy dermatoses: diagnosis, management, and controversies. Am J Clin Dermatol. 2011 Feb 1. 12(1):25-41. [QxMD MEDLINE Link].

6. Rudolph CM, Al-Fares S, Vaughan-Jones SA, Mullegger RR, Kerl H, Black MM. Polymorphic eruption of pregnancy: clinicopathology and potential trigger factors in 181 patients. Br J Dermatol. 2006 Jan. 154(1):54-60. [QxMD MEDLINE Link].

7. Kroumpouzos G, Cohen LM. Specific dermatoses of pregnancy: an evidence-based systematic review. Am J Obstet Gynecol. 2003 Apr. 188(4):1083-92. [QxMD MEDLINE Link].

8. Elling SV, McKenna P, Powell FC. Pruritic urticarial papules and plaques of pregnancy in twin and triplet pregnancies. J Eur Acad Dermatol Venereol. 2000 Sep. 14(5):378-81. [QxMD MEDLINE Link].

9. Dominguez-Serrano AJ, Quiroga-Garza A, Jacobo-Baca G, De La Fuente-Villarreal D, Gonzalez-Ramirez RA, Vazquez-Barragan MA, et al. Polymorphic eruption of pregnancy in Mexico. Int J Dermatol. 2019 Mar. 58 (3):259-262. [QxMD MEDLINE Link].

10. Ohel I, Levy A, Silberstein T, Holcberg G, Sheiner E. Pregnancy outcome of patients with pruritic urticarial papules and plaques of pregnancy. J Matern Fetal Neonatal Med. 2006 May. 19(5):305-8. [QxMD MEDLINE Link].

11. Vaughan Jones SA, Hern S, Nelson-Piercy C, Seed PT, Black MM. A prospective study of 200 women with dermatoses of pregnancy correlating clinical findings with hormonal and immunopathological profiles. Br J Dermatol. 1999 Jul. 141(1):71-81. [QxMD MEDLINE Link].

12. Aractingi S, Berkane N, Bertheau P, et al. Fetal DNA in skin of polymorphic eruptions of pregnancy. Lancet. 1998 Dec 12. 352(9144):1898-901. [QxMD MEDLINE Link].

13. Regnier S, Fermand V, Levy P, Uzan S, Aractingi S. A case-control study of polymorphic eruption of pregnancy. J Am Acad Dermatol. 2008 Jan. 58(1):63-7. [QxMD MEDLINE Link].

14. Dehdashti AL, Wikas SM. Pruritic urticarial papules and plaques of pregnancy occurring postpartum. Cutis. 2015 Jun. 95 (6):344-7. [QxMD MEDLINE Link].

15. Sherley-Dale AC, Carr RA, Charles-Holmes R. Polymorphic eruption of pregnancy with bullous lesions: a previously unreported association. Br J Dermatol. 2009 Nov 3. [QxMD MEDLINE Link].

16. Roger D, Vaillant L, Fignon A, et al. Specific pruritic diseases of pregnancy. A prospective study of 3192 pregnant women. Arch Dermatol. 1994 Jun. 130(6):734-9. [QxMD MEDLINE Link].

17. Sirikudta W, Silpa-Archa N. Polymorphic eruption of pregnancy presented with targetoid lesions: a report of two cases. Case Rep Dermatol. 2013 May. 5 (2):138-43. [QxMD MEDLINE Link].

18. Goolamali SI, Salisbury JR, Higgins EM. Polymorphic eruption of pregnancy in a photodistribution: a potentially new association?. Clin Exp Dermatol. 2009 Oct. 34(7):e381-2. [QxMD MEDLINE Link].

19. Bohdanowicz M, Ghazarian D, Rosen CF. Targetoid form of polymorphic eruption of pregnancy: A case report. SAGE Open Med Case Rep. 2019. 7:2050313X19882841. [QxMD MEDLINE Link].

20. Kanj RV, Gerber D, Frey MK, Rahmanou F, Hardy C. Anaplastic Large Cell Lymphoma in Pregnancy. A Case Report. J Reprod Med. 2015 May-Jun. 60 (5-6):265-8. [QxMD MEDLINE Link].

21. Powell AM, Sakuma-Oyama Y, Oyama N, et al. Usefulness of BP180 NC16a enzyme-linked immunosorbent assay in the serodiagnosis of pemphigoid gestationis and in differentiating between pemphigoid gestationis and pruritic urticarial papules and plaques of pregnancy. Arch Dermatol. 2005 Jun. 141(6):705-10. [QxMD MEDLINE Link].

22. Ahmadi S, Powell FC. Pruritic urticarial papules and plaques of pregnancy: current status. Australas J Dermatol. 2005 May. 46(2):53-8; quiz 59. [QxMD MEDLINE Link].

23. Scheinfeld N. Pruritic urticarial papules and plaques of pregnancy wholly abated with one week twice daily application of fluticasone propionate lotion: a case report and review of the literature. Dermatol Online J. 2008 Nov 15. 14(11):4. [QxMD MEDLINE Link].

24. Beltrani VP, Beltrani VS. Pruritic urticarial papules and plaques of pregnancy: a severe case requiring early delivery for relief of symptoms. J Am Acad Dermatol. 1992 Feb. 26(2 Pt 1):266-7. [QxMD MEDLINE Link].

25. Jeon IK, On HR, Oh SH, Hann SK. Three cases of pruritic urticarial papules and plaques of pregnancy (PUPPP) treated with intramuscular injection of autologous whole blood. J Eur Acad Dermatol Venereol. 2015 Apr. 29 (4):797-800. [QxMD MEDLINE Link].

Joseph C Pierson, MD Dermatology Residency Program Director, University of Vermont College of Medicine

Joseph C Pierson, MD is a member of the following medical societies: Association of Professors of Dermatology, New England Dermatological Society, American Academy of Dermatology

Disclosure: Nothing to disclose.

Christine C Tam, MD Managing Member, Certified Dermatologists

Christine C Tam, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

William D James, MD Paul R Gross Professor of Dermatology, Vice-Chairman, Residency Program Director, Department of Dermatology, University of Pennsylvania School of Medicine

William D James, MD is a member of the following medical societies: American Academy of Dermatology, Society for Investigative Dermatology

Disclosure: Received income in an amount equal to or greater than $250 from: Elsevier; WebMD<br/>Served as a speaker for various universities, dermatology societies, and dermatology departments.

David F Butler, MD Professor of Dermatology, Texas A&M University College of Medicine; Chair, Department of Dermatology, Director, Dermatology Residency Training Program, Scott and White Clinic, Northside Clinic

David F Butler, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American Medical Association, American Society for Dermatologic Surgery, American Society for MOHS Surgery, Association of Military Dermatologists, and Phi Beta Kappa

Disclosure: Nothing to disclose.

Edward F Chan, MD Clinical Assistant Professor, Department of Dermatology, University of Pennsylvania School of Medicine

Edward F Chan, MD is a member of the following medical societies: American Academy of Dermatology, American Society of Dermatopathology, and Society for Investigative Dermatology

Disclosure: Nothing to disclose.

Abdul-Ghani Kibbi, MD Professor and Chair, Department of Dermatology, American University of Beirut Medical Center, Lebanon

Disclosure: Nothing to disclose.

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