Cutaneous Kikuchi Disease Treatment & Management

Updated: Nov 14, 2019
  • Author: Jenny E Liles, MD; Chief Editor: Dirk M Elston, MD  more...
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Treatment

Medical Care

Once the diagnosis of Kikuchi disease (KD) is established, no specific medical care is indicated because this is a self-limited condition. NSAIDs or systemic steroids can be used if symptoms are severe as these may aid resolution. [35] Hydroxychloroquine is another option that has been effective in the treatment of KD. [36] It may be an especially good option for cutaneous KD or KD associated with lupus erythematosus. [3, 14] Hydroxychloroquine in combination with systemic steroids has also been used to successfully treat recurrent KD. [37, 38]

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Surgical Care

No surgical care is needed aside from performing a lymph node biopsy to make the diagnosis.

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Consultations

Consultation from a dermatologist, a pathologist, a surgeon, and an otolaryngologist can be helpful in establishing the diagnosis.

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Long-Term Monitoring

Long-term monitoring of patients with Kikuchi disease (KD) is required because KD carries a risk of progression to systemic and/or cutaneous lupus erythematosus. This risk ranges from 13-25% in the literature. [39] Therefore, patients should be warned of symptoms to watch for and should continue to see doctors regularly.

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