Cutaneous Manifestations of Hepatitis C Questions & Answers

Updated: Apr 02, 2020
  • Author: Robert A Schwartz, MD, MPH; Chief Editor: Dirk M Elston, MD  more...
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Questions & Answers

Overview

What is hepatitis C (Hep C)?

What is the prevalence of cutaneous symptoms of hepatitis C (Hep C)?

What are the most common extrahepatic manifestation of hepatitis C (Hep C)?

Why is hepatitis C virus (HCV) considered a major public health problem?

What are the primary and secondary causation of cutaneous symptoms of chronic hepatitis C (CHC)?

What is the tertiary causation of cutaneous symptoms of chronic hepatitis C (CHC)?

Which disorders associated with hepatitis C (Hep C) may cause cutaneous symptoms?

What are the genotypes of hepatitis C virus (HCV)?

What are possible secondary disorders of chronic hepatitis C (CHC)?

What is the pathogenesis of cutaneous manifestations in hepatitis C virus (HCV) infection?

What is the pathogenesis of lichen planus in hepatitis C virus (HCV)?

What is the pathogenesis of type II cryoglobulinemia in hepatitis C virus (HCV)?

What is sialadenitis in chronic hepatitis C (CHC)?

What is the pathogenesis of cryoglobulinemia due to chronic hepatitis C (CHC)?

What are the types of cryoglobulinemia caused by hepatitis C (Hep C)?

What causes sialadenitis in chronic hepatitis C (CHC)?

What is the pathogenesis of Mooren corneal ulcer in chronic hepatitis C (CHC)?

What causes antiphospholipid syndrome in chronic hepatitis C (CHC)?

What are tertiary dermatologic disorders of chronic hepatitis C (CHC)?

What causes Porphyria cutanea tarda (PCT) in chronic hepatitis C (CHC)?

What is Sjögren syndrome due to hepatitis C virus (HCV) infection?

What causes non-Hodgkin lymphoma in chronic hepatitis C (CHC)?

What is the possible genetic etiology squamous cell carcinoma in hepatitis C virus (HCV) infection?

What causes mucosa-associated lymphoma tumors (MALT) syndrome in chronic hepatitis C (CHC)?

What causes hepatoma in chronic hepatitis C (CHC)?

Which treatments for hepatitis C infection cause dermatologic symptoms?

What is the prevalence of hepatitis C (Hep C) in the US?

What is the global prevalence of hepatitis C (Hep C)?

Which patient groups are at increased risk for hepatitis C (Hep C)?

How does the prevalence of hepatitis C (Hep C) vary by age?

What is the prognosis of dermatologic manifestations of hepatitis C virus (HCV) infection?

What is the mortality and morbidity of hepatitis C (Hep C)?

Where can patient education resources about cutaneous manifestations of hepatitis C (Hep C) be found?

Presentation

What are the signs and symptoms of Behcet syndrome in hepatitis C (Hep C)?

What are the signs and symptoms of erythema multiforme in hepatitis C (Hep C)?

What is the disease progression of hepatitis C (Hep C)?

What are symptoms of chronic hepatitis C (CHC)?

What are the less specific dermatologic symptoms of hepatitis C (Hep C)?

How are pruritus and chronic hepatitis C (CHC) related?

What are the signs and symptoms of lichen planus in chronic hepatitis C (CHC)?

What are the signs and symptoms of acral necrolytic erythema in chronic hepatitis C (CHC)?

What are the signs and symptoms of sialadenitis in chronic hepatitis C (CHC)?

What is Mooren corneal ulceration in chronic hepatitis C (CHC)?

What are the signs and symptoms of leukocytoclastic reaction in chronic hepatitis C (CHC)?

What are the signs and symptoms of cryoglobulinemia in chronic hepatitis C (CHC)?

What are the signs and symptoms of sialadenitis and Mooren corneal ulcer in chronic hepatitis C (CHC)?

What are the signs and symptoms of antiphospholipid syndrome in chronic hepatitis C (CHC)?

What are the signs and symptoms of dermatologic disorders tertiary to chronic hepatitis C (CHC)?

What are the signs and symptoms of canities and prurigo (prurigo nodularis) in hepatitis C (Hep C)?

What are the signs and symptoms of polyarteritis nodosa (PAN) in hepatitis C (Hep C)?

What is the prevalence of pruritus in hepatitis C (Hep C)?

What is the prevalence of urticaria in hepatitis C (Hep C)?

What are the signs and symptoms of erythema nodosum in hepatitis C (Hep C)?

What are the signs and symptoms of autoimmune thrombocytopenia in hepatitis C (Hep C)?

What causes leukocytoclastic vasculitis in hepatitis C (Hep C)?

What are the signs and symptoms of porphyria cutanea tarda (PCT) in chronic hepatitis C (CHC)?

What is the prevalence of porphyria cutanea tarda (PCT) in chronic hepatitis C (CHC)?

What are the signs and symptoms of non-Hodgkin B-cell lymphoma in chronic hepatitis C (CHC) disease?

What is the prevalence of non-Hodgkin B-cell lymphoma (NHLB) in patients with hepatitis C virus (HCV) infection?

What is the clinical history of hepatoma in hepatitis C virus (HCV) infection?

What is the manifestation of squamous cell carcinoma in chronic hepatitis C (CHC) disease?

Which signs and symptoms suggest interferon alfa therapy-related cutaneous manifestation in patients with hepatitis C virus (HCV) infection?

Which dermatologic conditions may be present in patients with hepatitis C virus (HCV) infection?

What are other possible conditions associated with hepatitis C virus (HCV) infection?

Which physical findings are characteristic of lichen planus or acral necrolytic erythema in patients with hepatitis C (Hep C)?

Which physical findings are characteristic of leukocytoclastic reactions in patients with hepatitis C (Hep C)?

Which physical findings are characteristic of sialadenitis in patients with hepatitis C (Hep C)?

Which physical findings are characteristic of dermatologic disorders due to chronic hepatitis C (CHC) infection?

What autoimmune factors may be present on physical exam of patients with hepatitis C (Hep C)?

Which physical findings are characteristic of dermatologic disorders tertiary to hepatitis C virus (HCV) infection?

Which physical are characteristic of porphyria cutanea tarda (PCT) in patients with hepatitis C virus (HCV) infection?

Which physical findings are characteristic of malignancies in chronic hepatitis C (CHC) disease?

Which physical findings are characteristic of dermatologic reactions to hepatitis C (Hep C) treatment?

Which physical findings are characteristic of hemangioma in patients with hepatitis C (Hep C)?

What are the pregnancy risks in patients with hepatitis C (Hep C)?

DDX

What conditions should be included in the differential diagnosis of dermatologic manifestations of hepatitis C (Hep C)?

What are the differential diagnoses for Cutaneous Manifestations of Hepatitis C?

Workup

According to the Centers for Disease Control and Prevention (CDC) guidelines, who should be screened for hepatitis C?

Which lab tests should be performed in the evaluation of cutaneous manifestations of hepatitis C (Hep C)?

What is the role of histology in the evaluation of the cutaneous manifestations of hepatitis C (Hep C)?

Treatment

What is included in medical care for the cutaneous manifestations of hepatitis C (Hep C)?

What is the role of surgery in the treatment of the cutaneous manifestations of hepatitis C (Hep C)?

Which specialist consultations are necessary for the management of the cutaneous manifestations of hepatitis C (Hep C)?

What may cause premature therapy discontinuation in patients with hepatitis C (Hep C)?

How are the cutaneous manifestations of hepatitis C (Hep C) prevented?

What is included in the long-term monitoring of cutaneous manifestations of hepatitis C (Hep C)?

Guidelines

Which organizations have published treatment guidelines for hepatitis C (Hep C)?