Radial Mononeuropathy Treatment & Management

Updated: May 22, 2017
  • Author: Wayne E Anderson, DO, FAHS, FAAN; Chief Editor: Nicholas Lorenzo, MD, MHA, CPE  more...
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Medical Care

Therapy is dependent on the site and cause of the lesion.

  • When the lesion is due to external compression at the spiral groove, removing the source of the compression and conservative management is indicated.
  • Physical therapy and wrist splinting helps in reestablishing functional use of the hand.
  • If the lesion is due to a humeral fracture, the fracture must be carefully reduced and set to avoid further injury. This may require external fixation.
  • If no recovery is noted within several months, then exploration for the site of compression or transection with possible surgical re-anastomosis may be indicated. [12]
  • With posterior interosseous neuropathies, repetitive supination of the forearm should be avoided.
  • In distal radial sensory nerve lesions, management is typically conservative.

Surgical Care

Surgical exploration may be considered for a chronic compressive lesion or transection.

  • Surgical exploration frequently is indicated for release of the nerve from tethered points in the forearm.
  • Localizing the lesion prior to surgery via EMG is important to assist the surgeon in identifying which section of the nerve is most likely involved.
  • When transection is suspected as the mechanism of injury, conservative management for several months is indicated to assure that no nerve regrowth has occurred either clinically or by electrodiagnostic measures.
  • If no regeneration or inadequate regeneration is confirmed, surgical exploration with possible re-anastomosis may be indicated.
  • Selective tendon transfer may allow for finger extension and thumb extension in cases of long-standing, irreparable radial nerve lesions. [13, 14]
  • Consensus has not been reached regarding the need for and timing of surgical therapy to treat radial nerve palsy with accompanying humeral fracture. [15, 16, 17, 18]


Electrodiagnostic consultation is important in radial mononeuropathy in order to:

  • Localize the lesion
  • Provide useful prognostic information in traumatic radial neuropathy