Raeder Paratrigeminal Syndrome Workup

Updated: Aug 15, 2018
  • Author: Steven H Schechter, MD; Chief Editor: Robert A Egan, MD  more...
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Approach Considerations

As previously stated, because painful Horner syndrome can occur with other diseases, such as cluster headache and carotid dissection or aneurysm, a diagnosis of Raeder paratrigeminal syndrome should be made on clinical and radiologic grounds. [9]



Laboratory Studies

While most cases of Raeder paratrigeminal syndrome are benign, a thorough evaluation to exclude secondary causes may be warranted, particularly if parasellar nerve involvement is evident.

Basic laboratory analysis to evaluate for inflammatory or infectious etiologies also may be warranted.

A basic chemistry profile, a complete blood count (CBC), the erythrocyte sedimentation rate, antinuclear antibody, and rheumatoid factor may be helpful in screening for inflammatory or infectious causes.


Imaging Studies

The neurodiagnostic evaluation should include magnetic resonance imaging (MRI) and MR angiography (MRA) of the brain. These studies help to exclude secondary causes such as dissection, vascular anomaly, and aneurysm.

Cerebral arteriography may be considered if clinically indicated or if MRA findings warrant further evaluation.