Diffuse Sclerosis Questions & Answers

1. Schilder P. Zur Kenntnis der sogenannten diffusen Sklerose. Z Ges Neurol Psychiatr. 1912. 10:1-60.

2. Jarius S, Haas J, Paul F, Wildemann B. Myelinoclastic diffuse sclerosis (Schilder's disease) is immunologically distinct from multiple sclerosis: results from retrospective analysis of 92 lumbar punctures. J Neuroinflammation. 2019 Feb 28. 16 (1):51. [QxMD MEDLINE Link]. [Full Text].

3. Karussis D. The diagnosis of multiple sclerosis and the various related demyelinating syndromes: a critical review. J Autoimmun. 2014 Feb-Mar. 48-49:134-42. [QxMD MEDLINE Link].

4. Schilder P. Zur Frage der Encephalitis periaxialis diffusa. Z Ges Neurol Psychiatr. 1913. 15:359-76.

5. Schilder P. Die Encephalitis periaxialis diffusa. Arch Psychiatr. 1924. 71:327-356.

6. Poser CM. Myelinoclastic diffuse sclerosis. Handbook of Clinical Neurology. New York, NY: American Elsevier; 1985. Vol 3: 419-428.

7. Poser CM. Diffuse-disseminated sclerosis in the adult. J Neuropathol Exp Neurol. 1957. 16:61-78.

8. Schilder disease. Orphanet. Available at https://www.orpha.net/consor/cgi-bin/OC_Exp.php?Expert=59298. Accessed: July 2009.

9. Maraş Genç H, Kara B, Uyur Yalçın E, Sakarya Güneş A, Deniz A, Anık Y. Long-term clinical and radiologic follow-up of Schilder's disease. Mult Scler Relat Disord. 2017 Apr. 13:47-51. [QxMD MEDLINE Link].

10. Kraus D, Konen O, Straussberg R. Schilder's disease: Non-invasive diagnosis and successful treatment with human immunoglobulins. Eur J Paediatr Neurol. 2011 Sep 16. [QxMD MEDLINE Link].

11. Barbieri F, Filla A, Grossi D, Orefice G, Perretti A, Cirillo S, et al. Clinical and computerized tomographic study of a case of Schilder's disease. Acta Neurol (Napoli). 1982 Feb. 4(1):57-61. [QxMD MEDLINE Link].

12. Bielschowsky M, Henneberg R. Uber familiare diffuse Sklerose (Leukodystrophia cerebri progressiva hereditaria). J Psychol Neurol. 1928. 36:131-81.

13. Cala LA, Mastaglia FL. Computerised tomography findings in multiple sclerosis and Schilder's disease. Clin Exp Neurol. 1977. 14:229-36. [QxMD MEDLINE Link].

14. Cotrufo R, Salvati G, Morcaldi L, Giordano GG, Guazzi GC. [What is Schilder's disease? Biological study of an unusual neuro-endocrine process]. Riv Patol Nerv Ment. 1968 Apr. 89(2):133-52. [QxMD MEDLINE Link].

15. Dupel-Pottier C. [Diagnostic criteria of borderline forms of multiple sclerosis]. Rev Neurol (Paris). 2001 Sep. 157(8-9 Pt 2):935-43. [QxMD MEDLINE Link].

16. Fernández-Jaén A, Martínez-Bermejo A, Gutiérrez-Molina M, López-Martín V, Tendero A, Arcas J, et al. [Schilder's diffuse myelinoclastic sclerosis]. Rev Neurol. 2001 Jul 1-15. 33(1):16-21. [QxMD MEDLINE Link].

17. Ferrer I, Fábregves I, Alvarez EF, Vila J. Schilder's disease. A study of the cerebral cortex with Golgi's method. Childs Brain. 1981. 8(4):294-8. [QxMD MEDLINE Link].

18. Fogli A, Schiffmann R, Bertini E. The effect of genotype on the natural history of eIF2B-related leukodystrophies. Neurology. 2004 May 11. 62(9):1509-17. [QxMD MEDLINE Link].

19. Foix C, Marie J. La sclerose cerebrale centrolobaire a tendance symetrique. Encephale. 1927. 22:81-126.

20. Fontaine B. [Borderline forms of multiple sclerosis]. Rev Neurol (Paris). 2001 Sep. 157(8-9 Pt 2):929-34. [QxMD MEDLINE Link].

21. Haberfeld W, Spieler F. Zur diffusen Sklerose des Hirns und Ruckenmarks. Dtsch Z Nervenheilkd. 1910. 40:436-63.

22. Heubner O. Uber diffuse Hirnsklerose. Charite-Ann. 1897. 22:298-310.

23. Hogan EL, Joseph KC, Hurt JP, Krigman MR. Schilder's diffuse sclerosis: a biochemical and ultrastructural study of myelinoclastic demyelinaton. Acta Neuropathol. 1972. 20(2):85-95. [QxMD MEDLINE Link].

24. Iwanowski L, Jedrzejewska A, Dydyk L. [Transitional form of disseminated and diffuse sclerosis during the period of exacerbation]. Neuropatol Pol. 1972. 10(1):79-85. [QxMD MEDLINE Link].

25. Jankowski K. A case of Schilder's diffuse sclerosis diagnosed clinically schizophrenia. Acta Neuropathol. 1963. 2:302-305.

26. Kotil K, Kalayci M, Köseoglu T, Tugrul A. Myelinoclastic diffuse sclerosis (Schilder's disease): report of a case and review of the literature. Br J Neurosurg. 2002 Oct. 16(5):516-9. [QxMD MEDLINE Link].

27. Kurul S, Cakmakçi H, Dirik E, Kovanlikaya A. Schilder's disease: case study with serial neuroimaging. J Child Neurol. 2003 Jan. 18(1):58-61. [QxMD MEDLINE Link].

28. Lhermitte F, Escourolle R, Hauw JJ, Gray F, Serdaru M, Lyon-Caen O. [Necrotic aspects of multiple sclerosis and Schilder's disease (author's transl)]. Rev Neurol (Paris). 1981. 137(10):589-600. [QxMD MEDLINE Link].

29. Lumsden CE. Fundamental problems i the pathology of multiple sclerosis and allied demyelinating diseases. Br Med J. 1951. 1:1035-1043.

30. Marbrug O. Die sogenannte 'akute multiple Sklerose' (Encephalomyelitis periaxialis scleroticans). Jahrb Psychiatr Neurol. 1906. 27:211-312.

31. Marie P, Foix C. Triplegie spasmodique, sclerose intracerebrale centrolobaire et symetrique. Rev Neurol. 1913. 21:346.

32. Marks E, Miszczak J. [Case of late form of Schilder's disease]. Neurol Neurochir Pol. 1972 Mar-Apr. 6(2):301-3. [QxMD MEDLINE Link].

33. Miyagawa K, Ando S, Seino M, Murofushi K. [An autopsy case of inflammatory diffuse sclerosis (adult case of Schilder's disease)--clinicopathological study (author's transl)]. Seishin Shinkeigaku Zasshi. 1976 Dec. 78(12):815-28. [QxMD MEDLINE Link].

34. Norman MG, Waisberg HA, Lowden JA. Progressive deafness and dementia in an 8-year-old boy. J Pediatr. 1975 May. 86(5):805-9. [QxMD MEDLINE Link].

35. Pajak B, Stefanko S, Goldsztajn M. [Acute course of Schilder's disease]. Neurol Neurochir Pol. 1971. 5(2):233-6. [QxMD MEDLINE Link].

36. Picard E. Case records of the Massachusetts General Hospital. Case 43-1965. N Engl J Med. 1965 Sep 30. 273(14):760-7. [QxMD MEDLINE Link].

37. Poser CM. Disseminated vasculomyelinopathy. A review of the clinical and pathologic reactions of the nervous system in hyperergic diseases. Acta Neurol Scand. 1969. Suppl 37:3-44. [QxMD MEDLINE Link].

38. Poser CM. Myelinoclastic diffuse and transitional sclerosis. Handbook of Clinical Neurology. New York, NY: American Elsevier; 1970. Vol 9: 469-84.

39. Poser CM, Brinar VV. The nature of multiple sclerosis. Clin Neurol Neurosurg. 2004 Jun. 106(3):159-71. [QxMD MEDLINE Link].

40. Poser CM, Goutières F, Carpentier MA, Aicardi J. Schilder's myelinoclastic diffuse sclerosis. Pediatrics. 1986 Jan. 77(1):107-12. [QxMD MEDLINE Link].

41. Poser CM, Van Bogaert L. Natural history and evolution of the concept of Schilder's diffuse sclerosis. Acta Neurol Scand. 1956. 31:285-331.

42. Tanaka J, Garcia JH, Khurana R. Unusual demyelinating disease. A form of diffuse-disseminated sclerosis. Neurology. 1975 Jun. 25(6):588-93. [QxMD MEDLINE Link].

43. Van Bogaert L, De Busscher J. Sur la sclerose inflammatoire de la substance blanche des hemispheres. Rev Neurol. 1939. 71:679-701.

44. Van Gehuchten P, Brucher JM. La forme transitionelle de la sclerose cerebrale diffuse de Schilder. Rev Neurol. 1961. 104:108-125.

45. Vanden Herrewegen M, Chamoles N. [Recent study on the significance of diffuse sclerosis of the Schilder type (1912) in children. 1. Anatomoclinical aspect of a sporadic case]. Acta Neurol Psychiatr Belg. 1968 Nov. 68(11):837-50. [QxMD MEDLINE Link].

46. Walker E. Case records of the MGH - leukoencephalitis, diffuse sclerosis (Schilder's disease). N Engl J Med. 1962. 266:191-96.

47. Watanabe I, Muller J. Cavitating "diffuse sclerosis". J Neuropathol Exp Neurol. 1967 Jul. 26(3):437-55. [QxMD MEDLINE Link].

Emad R Noor, MBChB Assistant Professor of Neurology and Clinical Neurophysiology, Hackensack Meridian School of Medicine; Attending Neurologist/Clinical Neurophysiologist, Neuroscience Institute at JFK Medical Center

Emad R Noor, MBChB is a member of the following medical societies: American Academy of Neurology, American Medical Association, Egyptian Society of Neurology, Psychiatry, and Neurosurgery

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Niranjan N Singh, MBBS, MD, DM, FAHS, FAANEM Adjunct Associate Professor of Neurology, University of Missouri-Columbia School of Medicine; Medical Director of St Mary's Stroke Program, SSM Neurosciences Institute, SSM Health

Niranjan N Singh, MBBS, MD, DM, FAHS, FAANEM is a member of the following medical societies: American Academy of Neurology, American Association of Neuromuscular and Electrodiagnostic Medicine, American Headache Society

Disclosure: Nothing to disclose.

Robert Stanley Rust, Jr, MD, MA Former Thomas E Worrell Jr Professor of Epileptology and Neurology, Co-Director of FE Dreifuss Child Neurology and Epilepsy Clinics, Director, Child Neurology, University of Virginia School of Medicine; Chair-Elect, Child Neurology Section, American Academy of Neurology

Robert Stanley Rust, Jr, MD, MA is a member of the following medical societies: American Academy of Neurology, American Epilepsy Society, American Headache Society, American Neurological Association, Child Neurology Society, International Child Neurology Association, Society for Pediatric Research

Disclosure: Nothing to disclose.

William J Nowack, MD Associate Professor, Epilepsy Center, Department of Neurology, University of Kansas Medical Center

William J Nowack, MD is a member of the following medical societies: American Academy of Neurology, Biomedical Engineering Society, American Clinical Neurophysiology Society, American Epilepsy Society, EEG and Clinical Neuroscience Society, American Medical Informatics Association

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